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Gonadal dysfunction in morbidly obese adolescent girls.

dc.contributor.authorChin, Vivian
dc.contributor.authorCensani, Marisa
dc.contributor.authorLerner, Shulamit
dc.contributor.authorConroy, Rushika
dc.contributor.authorOberfield, Sharon
dc.contributor.authorMcMahon, Donald
dc.contributor.authorZitsman, Jeffrey
dc.contributor.authorFennoy, Ilene
dc.date.accessioned2023-05-12T17:11:40Z
dc.date.available2023-05-12T17:11:40Z
dc.date.issued2014-02-26
dc.identifier.citationChin V, Censani M, Lerner S, Conroy R, Oberfield S, McMahon D, Zitsman J, Fennoy I. Gonadal dysfunction in morbidly obese adolescent girls. Fertil Steril. 2014 Apr;101(4):1142-8. doi: 10.1016/j.fertnstert.2013.12.046. Epub 2014 Feb 26. PMID: 24581575; PMCID: PMC3972289.en_US
dc.identifier.eissn1556-5653
dc.identifier.doi10.1016/j.fertnstert.2013.12.046
dc.identifier.pmid24581575
dc.identifier.urihttp://hdl.handle.net/20.500.12648/8702
dc.description.abstractTo describe gonadal dysfunction and evaluate polycystic ovary syndrome (PCOS) and its association with metabolic syndrome (MeS) among girls in a morbidly obese adolescent population.
dc.description.abstractIn a cross-sectional study of 174 girls, height, weight, waist circumference, Tanner stage, reproductive hormones, carbohydrate and lipid markers, drug use, and menstrual history were obtained at baseline. Exclusion criteria were menarcheal age <2 years, hormonal contraceptive or metformin use, Tanner stage <4, and incomplete data on PCOS or MeS classification.
dc.description.abstractUniversity medical center outpatient clinic.
dc.description.abstractNinety-eight girls ages 13-19.6 years, Tanner 5, average body mass index of 46.6 kg/m(2), menarche at 11.4 years, and average menarcheal age of 5 years.
dc.description.abstractNone.
dc.description.abstractPolycystic ovary syndrome and MeS.
dc.description.abstractNinety-eight girls were divided into four groups: PCOS by National Institutes of Health criteria (PCOSN, n = 24), irregular menses only (n = 25), elevated T (≥55 ng/dL) only (n = 6), and obese controls (n = 43). Metabolic syndrome by modified Cook criteria affected 32 girls or 33% overall: 6 of 24 PCOSN, 7 of 25 irregular menses only, 4 of 6 elevated T only, and 15 of 43 obese controls. Polycystic ovary syndrome by National Institutes of Health criteria and its individual components were not associated with MeS after adjusting for body mass index.
dc.description.abstractUnlike obese adults, PCOSN and its individual components were not associated with MeS in the untreated morbidly obese adolescent population.
dc.language.isoenen_US
dc.relation.urlhttps://www.fertstert.org/article/S0015-0282(13)03482-1/fulltexten_US
dc.rightsCopyright © 2014 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectMetabolic syndromeen_US
dc.subjectbariatric surgeryen_US
dc.subjectmorbid obesityen_US
dc.subjectpolycystic ovary syndromeen_US
dc.titleGonadal dysfunction in morbidly obese adolescent girls.en_US
dc.typeArticle/Reviewen_US
dc.source.journaltitleFertility and sterilityen_US
dc.source.volume101
dc.source.issue4
dc.source.beginpage1142
dc.source.endpage8
dc.source.countryUnited States
dc.source.countryUnited States
dc.source.countryUnited States
dc.description.versionVoRen_US
refterms.dateFOA2023-05-12T17:11:40Z
html.description.abstractTo describe gonadal dysfunction and evaluate polycystic ovary syndrome (PCOS) and its association with metabolic syndrome (MeS) among girls in a morbidly obese adolescent population.
html.description.abstractIn a cross-sectional study of 174 girls, height, weight, waist circumference, Tanner stage, reproductive hormones, carbohydrate and lipid markers, drug use, and menstrual history were obtained at baseline. Exclusion criteria were menarcheal age <2 years, hormonal contraceptive or metformin use, Tanner stage <4, and incomplete data on PCOS or MeS classification.
html.description.abstractUniversity medical center outpatient clinic.
html.description.abstractNinety-eight girls ages 13-19.6 years, Tanner 5, average body mass index of 46.6 kg/m(2), menarche at 11.4 years, and average menarcheal age of 5 years.
html.description.abstractNone.
html.description.abstractPolycystic ovary syndrome and MeS.
html.description.abstractNinety-eight girls were divided into four groups: PCOS by National Institutes of Health criteria (PCOSN, n = 24), irregular menses only (n = 25), elevated T (≥55 ng/dL) only (n = 6), and obese controls (n = 43). Metabolic syndrome by modified Cook criteria affected 32 girls or 33% overall: 6 of 24 PCOSN, 7 of 25 irregular menses only, 4 of 6 elevated T only, and 15 of 43 obese controls. Polycystic ovary syndrome by National Institutes of Health criteria and its individual components were not associated with MeS after adjusting for body mass index.
html.description.abstractUnlike obese adults, PCOSN and its individual components were not associated with MeS in the untreated morbidly obese adolescent population.
dc.description.institutionSUNY Downstateen_US
dc.description.departmentPediatrics, Division of Pediatric Endocrinologyen_US
dc.description.degreelevelN/Aen_US
dc.identifier.journalFertility and sterility


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Copyright © 2014 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.
Except where otherwise noted, this item's license is described as Copyright © 2014 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.