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Comparison of A1C to Oral Glucose Tolerance Test for the Diagnosis of Prediabetes in Overweight and Obese Youth.

dc.contributor.authorKhokhar, Aditi
dc.contributor.authorNaraparaju, Gayathri
dc.contributor.authorFriedman, Miriam
dc.contributor.authorPerez-Colon, Sheila
dc.contributor.authorUmpaichitra, Vatcharapan
dc.contributor.authorChin, Vivian L
dc.date.accessioned2023-05-12T17:04:10Z
dc.date.available2023-05-12T17:04:10Z
dc.identifier.citationKhokhar A, Naraparaju G, Friedman M, Perez-Colon S, Umpaichitra V, Chin VL. Comparison of A1C to Oral Glucose Tolerance Test for the Diagnosis of Prediabetes in Overweight and Obese Youth. Clin Diabetes. 2017 Jul;35(3):133-140. doi: 10.2337/cd16-0037. PMID: 28761215; PMCID: PMC5510926.en_US
dc.identifier.issn0891-8929
dc.identifier.doi10.2337/cd16-0037
dc.identifier.pmid28761215
dc.identifier.urihttp://hdl.handle.net/20.500.12648/8700
dc.description.abstractThis study reports performance of A1C against the oral glucose tolerance test (OGTT) in predicting prediabetes among overweight and obese African-American and Caribbean children. A retrospective chart review was completed for 230 children. Receiver operating characteristic curves were generated to find the predictive performances of different tests against the OGTT. A1C alone is a poor discriminator of prediabetes in our study population, with low sensitivity (70%) and specificity (48.8%). BMI score, A1C, and homeostatic model assessment of insulin resistance are significant predictors of prediabetes and, when taken together, provide better discrimination for prediabetes.
dc.language.isoenen_US
dc.relation.urlhttps://diabetesjournals.org/clinical/article/35/3/133/35386/Comparison-of-A1C-to-Oral-Glucose-Tolerance-Testen_US
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.titleComparison of A1C to Oral Glucose Tolerance Test for the Diagnosis of Prediabetes in Overweight and Obese Youth.en_US
dc.typeArticle/Reviewen_US
dc.source.journaltitleClinical diabetes : a publication of the American Diabetes Associationen_US
dc.source.volume35
dc.source.issue3
dc.source.beginpage133
dc.source.endpage140
dc.source.countryUnited States
dc.source.countryUnited States
dc.description.versionVoRen_US
refterms.dateFOA2023-05-12T17:04:11Z
html.description.abstractThis study reports performance of A1C against the oral glucose tolerance test (OGTT) in predicting prediabetes among overweight and obese African-American and Caribbean children. A retrospective chart review was completed for 230 children. Receiver operating characteristic curves were generated to find the predictive performances of different tests against the OGTT. A1C alone is a poor discriminator of prediabetes in our study population, with low sensitivity (70%) and specificity (48.8%). BMI score, A1C, and homeostatic model assessment of insulin resistance are significant predictors of prediabetes and, when taken together, provide better discrimination for prediabetes.
dc.description.institutionSUNY Downstateen_US
dc.description.departmentPediatrics, Division of Pediatric Endocrinologyen_US
dc.description.degreelevelN/Aen_US
dc.identifier.journalClinical diabetes : a publication of the American Diabetes Association


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Attribution-NonCommercial-NoDerivatives 4.0 International
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivatives 4.0 International