Comparison of A1C to Oral Glucose Tolerance Test for the Diagnosis of Prediabetes in Overweight and Obese Youth.
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Author
Khokhar, AditiNaraparaju, Gayathri
Friedman, Miriam
Perez-Colon, Sheila
Umpaichitra, Vatcharapan
Chin, Vivian L
Journal title
Clinical diabetes : a publication of the American Diabetes AssociationPublication Volume
35Publication Issue
3Publication Begin page
133Publication End page
140
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This study reports performance of A1C against the oral glucose tolerance test (OGTT) in predicting prediabetes among overweight and obese African-American and Caribbean children. A retrospective chart review was completed for 230 children. Receiver operating characteristic curves were generated to find the predictive performances of different tests against the OGTT. A1C alone is a poor discriminator of prediabetes in our study population, with low sensitivity (70%) and specificity (48.8%). BMI score, A1C, and homeostatic model assessment of insulin resistance are significant predictors of prediabetes and, when taken together, provide better discrimination for prediabetes.Citation
Khokhar A, Naraparaju G, Friedman M, Perez-Colon S, Umpaichitra V, Chin VL. Comparison of A1C to Oral Glucose Tolerance Test for the Diagnosis of Prediabetes in Overweight and Obese Youth. Clin Diabetes. 2017 Jul;35(3):133-140. doi: 10.2337/cd16-0037. PMID: 28761215; PMCID: PMC5510926.DOI
10.2337/cd16-0037ae974a485f413a2113503eed53cd6c53
10.2337/cd16-0037
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- Creative Commons
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivatives 4.0 International
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