Show simple item record

dc.contributor.authorRosenbaum, Janet E
dc.contributor.authorOchoa, Kenny Castro
dc.contributor.authorHasan, Faria
dc.contributor.authorGoldfarb, Alexa
dc.contributor.authorTang, Vivian
dc.contributor.authorTomer, Gitit
dc.contributor.authorWallach, Thomas
dc.date.accessioned2023-03-02T17:18:25Z
dc.date.available2023-03-02T17:18:25Z
dc.date.issued2023-02-21
dc.identifier.citationRosenbaum JE, Ochoa KC, Hasan F, Goldfarb A, Tang V, Tomer G, Wallach T. Epidemiologic Assessment of Pediatric Inflammatory Bowel Disease Presentation in NYC During COVID-19. J Pediatr Gastroenterol Nutr. 2023 Feb 21:e003740. doi: 10.1097/MPG.0000000000003740. Epub ahead of print. PMID: 36805627.en_US
dc.identifier.eissn1536-4801
dc.identifier.doi10.1097/MPG.0000000000003740
dc.identifier.pmid36805627
dc.identifier.urihttp://hdl.handle.net/20.500.12648/8451
dc.description.abstractInflammatory Bowel Disease (IBD) pathogenesis is thought to be induced by a mix of genetic susceptibility, microbial populations, and immune triggers such as infections. SARS-nCoV2 may have increased capacity to generate autoimmune disease as evidenced by known spikes in diseases such as Type 1 Diabetes Mellitus. Public health interventions like masking and closures additionally created remarkable drops in typical viral infections, with remarkable shifts in ILI reporting in 2020. This study aims to evaluate the impact of SARS-nCoV2 and associated interventions on pediatric IBD presentation in NYC using records of new diagnoses at a consortium of four institutions between 2016 and June 2022. We fit time series model (ARIMA) to monthly and quarterly number of cases of each disease for January 2016-March 2020 and forecast the period between April 2020 and June 2022. We note no decrease in Ulcerative Colitis or Crohn's Disease in the aftermath of historic low levels of overall viral illness, and statistically significant increases in Crohn's Disease diagnoses and elevation in UC diagnoses creating a trend suggesting overall increase in IBD diagnoses exceeding the baseline rate of increase. These data suggest a possible linkage between SARS-nCoV2 infection rates and subsequent pediatric IBD presentation.
dc.language.isoenen_US
dc.relation.urlhttps://journals.lww.com/jpgn/Abstract/9900/Epidemiologic_Assessment_of_Pediatric_Inflammatory.298.aspxen_US
dc.rightsCopyright © 2023 by European Society for Pediatric Gastroenterology, Hepatology, and Nutrition and North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition.
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.titleEpidemiologic Assessment of Pediatric Inflammatory Bowel Disease Presentation in NYC During COVID-19.en_US
dc.typeArticle/Reviewen_US
dc.source.journaltitleJournal of pediatric gastroenterology and nutritionen_US
dc.source.countryUnited States
dc.description.versionAMen_US
html.description.abstractInflammatory Bowel Disease (IBD) pathogenesis is thought to be induced by a mix of genetic susceptibility, microbial populations, and immune triggers such as infections. SARS-nCoV2 may have increased capacity to generate autoimmune disease as evidenced by known spikes in diseases such as Type 1 Diabetes Mellitus. Public health interventions like masking and closures additionally created remarkable drops in typical viral infections, with remarkable shifts in ILI reporting in 2020. This study aims to evaluate the impact of SARS-nCoV2 and associated interventions on pediatric IBD presentation in NYC using records of new diagnoses at a consortium of four institutions between 2016 and June 2022. We fit time series model (ARIMA) to monthly and quarterly number of cases of each disease for January 2016-March 2020 and forecast the period between April 2020 and June 2022. We note no decrease in Ulcerative Colitis or Crohn's Disease in the aftermath of historic low levels of overall viral illness, and statistically significant increases in Crohn's Disease diagnoses and elevation in UC diagnoses creating a trend suggesting overall increase in IBD diagnoses exceeding the baseline rate of increase. These data suggest a possible linkage between SARS-nCoV2 infection rates and subsequent pediatric IBD presentation.
dc.description.institutionSUNY Downstateen_US
dc.description.departmentEpidemiology and Biostatisticsen_US
dc.description.degreelevelN/Aen_US
dc.identifier.journalJournal of pediatric gastroenterology and nutrition


Files in this item

Thumbnail
Name:
JPGN Accepted version.pdf
Size:
576.0Kb
Format:
PDF

This item appears in the following Collection(s)

Show simple item record

Copyright © 2023 by European Society for Pediatric Gastroenterology, Hepatology, and Nutrition and North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition.
Except where otherwise noted, this item's license is described as Copyright © 2023 by European Society for Pediatric Gastroenterology, Hepatology, and Nutrition and North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition.