Telling truth from Ys: an evaluation of whether the accuracy of self-reported semen exposure assessed by a semen Y-chromosome biomarker predicts pregnancy in a longitudinal cohort study of pregnancy.
dc.contributor.author | Rosenbaum, Janet E | |
dc.contributor.author | Zenilman, Jonathan | |
dc.contributor.author | Melendez, Johan | |
dc.contributor.author | Rose, Eve | |
dc.contributor.author | Wingood, Gina | |
dc.contributor.author | DiClemente, Ralph | |
dc.date.accessioned | 2023-03-01T19:46:37Z | |
dc.date.available | 2023-03-01T19:46:37Z | |
dc.date.issued | 2014-03-13 | |
dc.identifier.citation | Rosenbaum JE, Zenilman J, Melendez J, Rose E, Wingood G, DiClemente R. Telling truth from Ys: an evaluation of whether the accuracy of self-reported semen exposure assessed by a semen Y-chromosome biomarker predicts pregnancy in a longitudinal cohort study of pregnancy. Sex Transm Infect. 2014 Sep;90(6):479-84. doi: 10.1136/sextrans-2013-051315. Epub 2014 Mar 13. PMID: 24627289; PMCID: PMC4929791. | en_US |
dc.identifier.eissn | 1472-3263 | |
dc.identifier.doi | 10.1136/sextrans-2013-051315 | |
dc.identifier.pmid | 24627289 | |
dc.identifier.uri | http://hdl.handle.net/20.500.12648/8436 | |
dc.description.abstract | Adolescents may use condoms inconsistently or incorrectly, or may over-report condom use. This study used a semen exposure biomarker to evaluate the accuracy of female adolescents' reports of condom use and predict subsequent pregnancy. | |
dc.description.abstract | The sample comprised 715 sexually active African-American female adolescents, ages 15-21 years. At baseline, 6 months and 12 months, participants completed a 40-min interview and were tested for semen Y-chromosome with PCR from a self-administered vaginal swab. We predicted pregnancy from semen exposure under-report using multivariate regression controlling for oral contraception, reported condom use and coital frequency. | |
dc.description.abstract | At the 3 surveys, 30%, 20% and 15% of adolescents who reported always using condoms tested positive for semen exposure. At 6 month follow-up, 20.4% and 16.2% of the adolescents who under-reported semen exposure reported pregnancy, a higher pregnancy rate than accurate reporters of semen exposure, even accurate reporters who reported never using condoms (14.2% and 11.8%). Under-reporters of semen exposure were 3.23 (95% CI (1.61, 6.45)) times as likely to become pregnant at 6-month follow-up and 2.21 (0.94, 5.20) times as likely to become pregnant at 12-month follow-up as accurate reporters who reported not using contraception, adjusting for self-reported coital frequency. | |
dc.description.abstract | Adolescents who under-report semen exposure may be at uniquely high risk for unplanned pregnancy and STIs, and may also under-report coital frequency. Condom efficacy trials that rely on self-report may yield inaccurate results. Adapted to a clinical setting, the Y-chromosome PCR could alert women to incorrect or inconsistent condom use. | |
dc.language.iso | en | en_US |
dc.relation.url | https://sti.bmj.com/content/90/6/479.long | en_US |
dc.rights | Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions. | |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 International | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.subject | Adolescent | en_US |
dc.subject | Condoms | en_US |
dc.subject | Contraception | en_US |
dc.subject | DNA Amplification | en_US |
dc.subject | Pregnancy | en_US |
dc.title | Telling truth from Ys: an evaluation of whether the accuracy of self-reported semen exposure assessed by a semen Y-chromosome biomarker predicts pregnancy in a longitudinal cohort study of pregnancy. | en_US |
dc.type | Article/Review | en_US |
dc.source.journaltitle | Sexually transmitted infections | en_US |
dc.source.volume | 90 | |
dc.source.issue | 6 | |
dc.source.beginpage | 479 | |
dc.source.endpage | 84 | |
dc.source.country | United States | |
dc.source.country | United States | |
dc.source.country | United States | |
dc.source.country | United States | |
dc.source.country | United States | |
dc.source.country | England | |
dc.description.version | AM | en_US |
refterms.dateFOA | 2023-03-01T19:46:37Z | |
html.description.abstract | Adolescents may use condoms inconsistently or incorrectly, or may over-report condom use. This study used a semen exposure biomarker to evaluate the accuracy of female adolescents' reports of condom use and predict subsequent pregnancy. | |
html.description.abstract | The sample comprised 715 sexually active African-American female adolescents, ages 15-21 years. At baseline, 6 months and 12 months, participants completed a 40-min interview and were tested for semen Y-chromosome with PCR from a self-administered vaginal swab. We predicted pregnancy from semen exposure under-report using multivariate regression controlling for oral contraception, reported condom use and coital frequency. | |
html.description.abstract | At the 3 surveys, 30%, 20% and 15% of adolescents who reported always using condoms tested positive for semen exposure. At 6 month follow-up, 20.4% and 16.2% of the adolescents who under-reported semen exposure reported pregnancy, a higher pregnancy rate than accurate reporters of semen exposure, even accurate reporters who reported never using condoms (14.2% and 11.8%). Under-reporters of semen exposure were 3.23 (95% CI (1.61, 6.45)) times as likely to become pregnant at 6-month follow-up and 2.21 (0.94, 5.20) times as likely to become pregnant at 12-month follow-up as accurate reporters who reported not using contraception, adjusting for self-reported coital frequency. | |
html.description.abstract | Adolescents who under-report semen exposure may be at uniquely high risk for unplanned pregnancy and STIs, and may also under-report coital frequency. Condom efficacy trials that rely on self-report may yield inaccurate results. Adapted to a clinical setting, the Y-chromosome PCR could alert women to incorrect or inconsistent condom use. | |
dc.description.institution | SUNY Downstate | en_US |
dc.description.department | Epidemiology and Biostatistics | en_US |
dc.description.degreelevel | N/A | en_US |
dc.identifier.journal | Sexually transmitted infections |