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dc.contributor.authorKupferman, Juan C
dc.contributor.authorRosenbaum, Janet E
dc.contributor.authorLande, Marc B
dc.contributor.authorStabouli, Stella
dc.contributor.authorWang, Yongsheng
dc.contributor.authorForman, Daniella
dc.contributor.authorZafeiriou, Dimitrios I
dc.contributor.authorPavlakis, Steven G
dc.date.accessioned2023-03-01T19:04:09Z
dc.date.available2023-03-01T19:04:09Z
dc.date.issued2022-09-15
dc.identifier.citationKupferman JC, Rosenbaum JE, Lande MB, Stabouli S, Wang Y, Forman D, Zafeiriou DI, Pavlakis SG. Blood pressure in children with sickle cell disease is higher than in the general pediatric population. BMC Pediatr. 2022 Sep 15;22(1):549. doi: 10.1186/s12887-022-03584-9. PMID: 36109730; PMCID: PMC9476310.en_US
dc.identifier.eissn1471-2431
dc.identifier.doi10.1186/s12887-022-03584-9
dc.identifier.pmid36109730
dc.identifier.urihttp://hdl.handle.net/20.500.12648/8418
dc.description.abstractSickle cell disease (SCD) is associated with an increased risk of cardiovascular disease that may be due to a variety of possible risk factors, including abnormal blood pressure. Blood pressure (BP) of children and adolescents with SCD has been reported to be lower compared to the BP of the general pediatric population.
dc.description.abstractTo confirm this prior observation, we compared reference BP values for children with SCD with reference BP values of the general pediatric population. We hypothesized that children with SCD do not have lower BPs than children without SCD.
dc.description.abstractSystolic BP differed for both males and females, over the different age groups between pediatric subjects with and without SCD. Systolic BP was higher in children with SCD, in both obese and non-obese populations. Diastolic BP did not differ between the groups.
dc.description.abstractOur analysis demonstrated that systolic BP values are indeed higher in children with SCD than in the general pediatric population. This finding is consistent with the most recent literature showing abnormal BP patterns in the SCD pediatric population utilizing 24-hour BP monitoring devices. This is an important step for recognizing abnormal BP as a risk factor for cardio- and neurovascular events in SCD.
dc.language.isoenen_US
dc.relation.urlhttps://bmcpediatr.biomedcentral.com/articles/10.1186/s12887-022-03584-9en_US
dc.rights© 2022. The Author(s).
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectChildhooden_US
dc.subjectHypertensionen_US
dc.subjectPediatric hematology/oncologyen_US
dc.subjectPediatricsen_US
dc.subjectSickle cell Anemiaen_US
dc.subjectSystolicen_US
dc.titleBlood pressure in children with sickle cell disease is higher than in the general pediatric population.en_US
dc.typeArticle/Reviewen_US
dc.source.journaltitleBMC pediatricsen_US
dc.source.volume22
dc.source.issue1
dc.source.beginpage549
dc.source.endpage
dc.source.countryEngland
dc.description.versionVoRen_US
refterms.dateFOA2023-03-01T19:04:09Z
html.description.abstractSickle cell disease (SCD) is associated with an increased risk of cardiovascular disease that may be due to a variety of possible risk factors, including abnormal blood pressure. Blood pressure (BP) of children and adolescents with SCD has been reported to be lower compared to the BP of the general pediatric population.
html.description.abstractTo confirm this prior observation, we compared reference BP values for children with SCD with reference BP values of the general pediatric population. We hypothesized that children with SCD do not have lower BPs than children without SCD.
html.description.abstractSystolic BP differed for both males and females, over the different age groups between pediatric subjects with and without SCD. Systolic BP was higher in children with SCD, in both obese and non-obese populations. Diastolic BP did not differ between the groups.
html.description.abstractOur analysis demonstrated that systolic BP values are indeed higher in children with SCD than in the general pediatric population. This finding is consistent with the most recent literature showing abnormal BP patterns in the SCD pediatric population utilizing 24-hour BP monitoring devices. This is an important step for recognizing abnormal BP as a risk factor for cardio- and neurovascular events in SCD.
dc.description.institutionSUNY Downstateen_US
dc.description.departmentEpidemiology and Biostatisticsen_US
dc.description.degreelevelN/Aen_US
dc.identifier.journalBMC pediatrics


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