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dc.contributor.authorKuperman, Samuel
dc.contributor.authorChan, Grace
dc.contributor.authorKramer, John R
dc.contributor.authorWetherill, Leah
dc.contributor.authorBucholz, Kathleen K
dc.contributor.authorDick, Danielle
dc.contributor.authorHesselbrock, Victor
dc.contributor.authorPorjesz, Bernice
dc.contributor.authorRangaswamy, Madhavi
dc.contributor.authorSchuckit, Marc
dc.date.accessioned2023-02-01T18:51:16Z
dc.date.available2023-02-01T18:51:16Z
dc.date.issued2013-01-06
dc.identifier.citationKuperman S, Chan G, Kramer JR, Wetherill L, Bucholz KK, Dick D, Hesselbrock V, Porjesz B, Rangaswamy M, Schuckit M. A model to determine the likely age of an adolescent's first drink of alcohol. Pediatrics. 2013 Feb;131(2):242-8. doi: 10.1542/peds.2012-0880. Epub 2013 Jan 6. PMID: 23296431; PMCID: PMC3557403.en_US
dc.identifier.eissn1098-4275
dc.identifier.doi10.1542/peds.2012-0880
dc.identifier.pmid23296431
dc.identifier.urihttp://hdl.handle.net/20.500.12648/8186
dc.description.abstractWith the use of a new cohort of adolescent subjects, predictors from the Semi-Structured Assessment for the Genetics of Alcoholism (SSAGA) interview and the Achenbach Youth Self Report (YSR) were combined to model age of first drink (AFD).
dc.description.abstractSubjects consisted of 820 adolescents (ages 14-17) drawn from the current phase of the Collaborative Study on the Genetics of Alcoholism. Three Cox proportional hazards models were considered. Model 1 contained SSAGA variables equivalent to AFD predictors from our previous study: interview age, family history of alcohol dependence, and number of conduct disorder symptoms. Model 2 incorporated 2 additional SSAGA questions (best friends drink and smoked a cigarette before a reported AFD) plus 8 YSR-derived scale scores. Model 3 was a reduced version of model 2, retaining only significant predictors.
dc.description.abstractModel 2 was a significant improvement over model 1. Model 3 was the best and the most parsimonious of the 3 with respect to likelihood ratio and Wald χ(2) tests and retained only 5 variables from model 2. Included variables were the following: (1) best friends drink, (2) membership in a high-risk alcohol dependence family, (3) number of conduct disorder symptoms, (4) YSR externalizing score, and (5) YSR social problems score.
dc.description.abstractAdding variables to those from our original study improved our ability to model the likely age of alcohol initiation. In addition to the SSAGA, the YSR appears to have utility as a research tool to predict the age of alcohol initiation.
dc.language.isoenen_US
dc.relation.urlhttps://publications.aap.org/pediatrics/article-abstract/131/2/242/31898/A-Model-to-Determine-the-Likely-Age-of-anen_US
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.titleA model to determine the likely age of an adolescent's first drink of alcohol.en_US
dc.typeArticle/Reviewen_US
dc.source.journaltitlePediatricsen_US
dc.source.volume131
dc.source.issue2
dc.source.beginpage242
dc.source.endpage8
dc.source.countryUnited States
dc.source.countryUnited States
dc.source.countryUnited States
dc.description.versionVoRen_US
refterms.dateFOA2023-02-01T18:51:16Z
html.description.abstractWith the use of a new cohort of adolescent subjects, predictors from the Semi-Structured Assessment for the Genetics of Alcoholism (SSAGA) interview and the Achenbach Youth Self Report (YSR) were combined to model age of first drink (AFD).
html.description.abstractSubjects consisted of 820 adolescents (ages 14-17) drawn from the current phase of the Collaborative Study on the Genetics of Alcoholism. Three Cox proportional hazards models were considered. Model 1 contained SSAGA variables equivalent to AFD predictors from our previous study: interview age, family history of alcohol dependence, and number of conduct disorder symptoms. Model 2 incorporated 2 additional SSAGA questions (best friends drink and smoked a cigarette before a reported AFD) plus 8 YSR-derived scale scores. Model 3 was a reduced version of model 2, retaining only significant predictors.
html.description.abstractModel 2 was a significant improvement over model 1. Model 3 was the best and the most parsimonious of the 3 with respect to likelihood ratio and Wald χ(2) tests and retained only 5 variables from model 2. Included variables were the following: (1) best friends drink, (2) membership in a high-risk alcohol dependence family, (3) number of conduct disorder symptoms, (4) YSR externalizing score, and (5) YSR social problems score.
html.description.abstractAdding variables to those from our original study improved our ability to model the likely age of alcohol initiation. In addition to the SSAGA, the YSR appears to have utility as a research tool to predict the age of alcohol initiation.
dc.description.institutionSUNY Downstateen_US
dc.description.departmentHenri Begleiter Neurodynamics Laboratoryen_US
dc.description.degreelevelN/Aen_US
dc.identifier.journalPediatrics


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