A model to determine the likely age of an adolescent's first drink of alcohol.
Average rating
Cast your vote
You can rate an item by clicking the amount of stars they wish to award to this item.
When enough users have cast their vote on this item, the average rating will also be shown.
Star rating
Your vote was cast
Thank you for your feedback
Thank you for your feedback
Author
Kuperman, SamuelChan, Grace
Kramer, John R
Wetherill, Leah
Bucholz, Kathleen K
Dick, Danielle
Hesselbrock, Victor
Porjesz, Bernice
Rangaswamy, Madhavi
Schuckit, Marc
Journal title
PediatricsDate Published
2013-01-06Publication Volume
131Publication Issue
2Publication Begin page
242Publication End page
8
Metadata
Show full item recordAbstract
With the use of a new cohort of adolescent subjects, predictors from the Semi-Structured Assessment for the Genetics of Alcoholism (SSAGA) interview and the Achenbach Youth Self Report (YSR) were combined to model age of first drink (AFD).Subjects consisted of 820 adolescents (ages 14-17) drawn from the current phase of the Collaborative Study on the Genetics of Alcoholism. Three Cox proportional hazards models were considered. Model 1 contained SSAGA variables equivalent to AFD predictors from our previous study: interview age, family history of alcohol dependence, and number of conduct disorder symptoms. Model 2 incorporated 2 additional SSAGA questions (best friends drink and smoked a cigarette before a reported AFD) plus 8 YSR-derived scale scores. Model 3 was a reduced version of model 2, retaining only significant predictors.
Model 2 was a significant improvement over model 1. Model 3 was the best and the most parsimonious of the 3 with respect to likelihood ratio and Wald χ(2) tests and retained only 5 variables from model 2. Included variables were the following: (1) best friends drink, (2) membership in a high-risk alcohol dependence family, (3) number of conduct disorder symptoms, (4) YSR externalizing score, and (5) YSR social problems score.
Adding variables to those from our original study improved our ability to model the likely age of alcohol initiation. In addition to the SSAGA, the YSR appears to have utility as a research tool to predict the age of alcohol initiation.
Citation
Kuperman S, Chan G, Kramer JR, Wetherill L, Bucholz KK, Dick D, Hesselbrock V, Porjesz B, Rangaswamy M, Schuckit M. A model to determine the likely age of an adolescent's first drink of alcohol. Pediatrics. 2013 Feb;131(2):242-8. doi: 10.1542/peds.2012-0880. Epub 2013 Jan 6. PMID: 23296431; PMCID: PMC3557403.DOI
10.1542/peds.2012-0880ae974a485f413a2113503eed53cd6c53
10.1542/peds.2012-0880
Scopus Count
Collections
The following license files are associated with this item:
- Creative Commons
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivatives 4.0 International
Related articles
- A GABRA2 polymorphism improves a model for prediction of drinking initiation.
- Authors: Kuperman S, Chan G, Kramer J, Wetherill L, Acion L, Edenberg HJ, Foroud TM, Nurnberger J Jr, Agrawal A, Anokhin A, Brooks A, Hesselbrock V, Hesselbrock M, Schuckit M, Tischfield J, Liu X
- Issue date: 2017 Sep
- Relationship of age of first drink to child behavioral problems and family psychopathology.
- Authors: Kuperman S, Chan G, Kramer JR, Bierut L, Bucholz KK, Fox L, Hesselbrock V, Numberger JI Jr, Reich T, Reich W, Schuckit MA, Collaborative Study on the Genetics of Alcoholism
- Issue date: 2005 Oct
- The ability of the Self-Rating of the Effects of Alcohol (SRE) Scale to predict alcohol-related outcomes five years later.
- Authors: Schuckit MA, Smith TL, Danko GP, Pierson J, Hesselbrock V, Bucholz KK, Kramer J, Kuperman S, Dietiker C, Brandon R, Chan G
- Issue date: 2007 May
- The relationship between alcohol problems and dependence, conduct problems and diagnosis, and number of sex partners in a sample of young adults.
- Authors: Cavazos-Rehg PA, Spitznagel EL, Bucholz KK, Norberg K, Reich W, Nurnberger J Jr, Hesselbrock V, Kramer J, Kuperman S, Bierut LJ
- Issue date: 2007 Dec
- Does conduct disorder mediate the development of substance use disorders in adolescents with bipolar disorder? A case-control family study.
- Authors: Wilens TE, Martelon M, Kruesi MJ, Parcell T, Westerberg D, Schillinger M, Gignac M, Biederman J
- Issue date: 2009 Feb