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The soymilk diet: A previously unknown etiology of acute pancreatitis.

dc.contributor.authordeSouza, Ian S
dc.contributor.authorLipsitt, Alexander
dc.date.accessioned2023-01-30T16:59:28Z
dc.date.available2023-01-30T16:59:28Z
dc.date.issued2021-01-27
dc.identifier.citationdeSouza IS, Lipsitt A. The soymilk diet: A previously unknown etiology of acute pancreatitis. Am J Emerg Med. 2021 Aug;46:798.e5-798.e6. doi: 10.1016/j.ajem.2021.01.055. Epub 2021 Jan 27. PMID: 33546956.en_US
dc.identifier.eissn1532-8171
dc.identifier.doi10.1016/j.ajem.2021.01.055
dc.identifier.pmid33546956
dc.identifier.urihttp://hdl.handle.net/20.500.12648/8171
dc.description.abstractWe present a case of daily, large ingestions of soymilk that likely led to acute pancreatitis. Soybean contains trypsin inhibitor that when ingested will reduce the activity of trypsin in the intestine. A decrease in intestinal proteolytic activity removes the negative feedback on the pancreatic acinar cells, leading to an inappropriate increase in intrapancreatic trypsin secretion. When trypsin activation exceeds the capacity of pancreatic secretory trypsin inhibitor, the subsequent cascade of events can lead to acute pancreatitis.
dc.language.isoenen_US
dc.relation.urlhttps://www.sciencedirect.com/science/article/abs/pii/S0735675721000589?via%3Dihuben_US
dc.rightsCopyright © 2021 Elsevier Inc. All rights reserved.
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectPancreatic secretory trypsin inhibitoren_US
dc.subjectPancreatitisen_US
dc.subjectSoymilken_US
dc.subjectTrypsin inhibitoren_US
dc.subjectTrypsinogenen_US
dc.titleThe soymilk diet: A previously unknown etiology of acute pancreatitis.en_US
dc.typeArticle/Reviewen_US
dc.source.journaltitleThe American journal of emergency medicineen_US
dc.source.volume46
dc.source.beginpage798.e5
dc.source.endpage798.e6
dc.source.countryUnited States
dc.description.versionAMen_US
refterms.dateFOA2023-01-30T16:59:28Z
html.description.abstractWe present a case of daily, large ingestions of soymilk that likely led to acute pancreatitis. Soybean contains trypsin inhibitor that when ingested will reduce the activity of trypsin in the intestine. A decrease in intestinal proteolytic activity removes the negative feedback on the pancreatic acinar cells, leading to an inappropriate increase in intrapancreatic trypsin secretion. When trypsin activation exceeds the capacity of pancreatic secretory trypsin inhibitor, the subsequent cascade of events can lead to acute pancreatitis.
dc.description.institutionSUNY Downstateen_US
dc.description.departmentEmergency Medicineen_US
dc.description.degreelevelN/Aen_US
dc.identifier.journalThe American journal of emergency medicine


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Copyright © 2021 Elsevier Inc. All rights reserved.
Except where otherwise noted, this item's license is described as Copyright © 2021 Elsevier Inc. All rights reserved.