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dc.contributor.authorSalvatore, Jessica E
dc.contributor.authorDick, Danielle M
dc.date.accessioned2023-01-23T20:15:45Z
dc.date.available2023-01-23T20:15:45Z
dc.identifier.citationSalvatore JE, Dick DM. Gene-Environment Interplay: Where We Are, Where We Are Going. J Marriage Fam. 2015 Apr;77(2):344-350. doi: 10.1111/jomf.12164. PMID: 25838604; PMCID: PMC4378262.en_US
dc.identifier.issn0022-2445
dc.identifier.pmid25838604
dc.identifier.urihttp://hdl.handle.net/20.500.12648/8141
dc.description.abstractThe idea that both genetic and environmental influences contribute to behavioral outcomes is widely accepted. However, the practice of examining candidate Gene × Environment interaction (cGxE) is controversial. In this article, we summarize some of the key issues involved in cGxE research and provide recommendations for work in this area. Highlighted challenges include the selection of the gene, the development of the cGxE hypothesis, and the coding of the genotype. To address these challenges and gain confidence in cGxE findings, we recommend using empirical data to select and code genes/variants, using theory to develop cGxE hypotheses and a rigorous and transparent approach to hypothesis testing. Family researchers have much to offer to the study of Gene × Environment research in view of their process-oriented theories that are grounded in decades of nuanced measurement of the environment; implementing these best practices will help deliver on that promise.
dc.language.isoenen_US
dc.relation.urlhttps://onlinelibrary.wiley.com/doi/10.1111/jomf.12164en_US
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectdevelopmental psychologyen_US
dc.subjectfamily researchen_US
dc.subjectmeasurementen_US
dc.subjectmethodsen_US
dc.subjectresearch methodologiesen_US
dc.titleGene-Environment Interplay: Where We Are, Where We Are Going.en_US
dc.typeArticle/Reviewen_US
dc.source.journaltitleJournal of marriage and the familyen_US
dc.source.volume77
dc.source.issue2
dc.source.beginpage344
dc.source.endpage350
dc.source.countryUnited States
dc.source.countryUnited States
dc.source.countryUnited States
dc.source.countryUnited States
dc.source.countryUnited States
dc.source.countryUnited States
dc.description.versionAMen_US
refterms.dateFOA2023-01-23T20:15:45Z
html.description.abstractThe idea that both genetic and environmental influences contribute to behavioral outcomes is widely accepted. However, the practice of examining candidate Gene × Environment interaction (cGxE) is controversial. In this article, we summarize some of the key issues involved in cGxE research and provide recommendations for work in this area. Highlighted challenges include the selection of the gene, the development of the cGxE hypothesis, and the coding of the genotype. To address these challenges and gain confidence in cGxE findings, we recommend using empirical data to select and code genes/variants, using theory to develop cGxE hypotheses and a rigorous and transparent approach to hypothesis testing. Family researchers have much to offer to the study of Gene × Environment research in view of their process-oriented theories that are grounded in decades of nuanced measurement of the environment; implementing these best practices will help deliver on that promise.
dc.description.institutionSUNY Downstateen_US
dc.description.departmentHenri Begleiter Neurodynamics Laboratoryen_US
dc.description.degreelevelN/Aen_US
dc.identifier.journalJournal of marriage and the family


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