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dc.contributor.authorChester, David S
dc.contributor.authorBucholz, Kathleen K
dc.contributor.authorChan, Grace
dc.contributor.authorKamarajan, Chella
dc.contributor.authorPandey, Ashwini K
dc.contributor.authorWetherill, Leah
dc.contributor.authorKramer, John R
dc.contributor.authorNurnberger, John I
dc.contributor.authorSalvatore, Jessica E
dc.contributor.authorDick, Danielle M
dc.date.accessioned2022-12-05T19:06:48Z
dc.date.available2022-12-05T19:06:48Z
dc.date.issued2020-08-06
dc.identifier.citationChester DS, Bucholz KK, Chan G, Kamarajan C, Pandey AK, Wetherill L, Kramer JR, Nurnberger JI Jr, Salvatore JE, Dick DM. Alcohol-Related, Drug-Related, and Non-Substance-Related Aggression: 3 Facets of a Single Construct or 3 Distinct Constructs? Alcohol Clin Exp Res. 2020 Sep;44(9):1852-1861. doi: 10.1111/acer.14412. Epub 2020 Aug 6. PMID: 32761940; PMCID: PMC7722121.en_US
dc.identifier.eissn1530-0277
dc.identifier.doi10.1111/acer.14412
dc.identifier.pmid32761940
dc.identifier.urihttp://hdl.handle.net/20.500.12648/7916
dc.description.abstractBackground: Aggression often occurs alongside alcohol and drug misuse. However, it is not clear whether the latent and manifest relations among alcohol-related, drug-related, and non-substance-related aggression are separate manifestations of a single construct or instead are 3 distinct constructs. Methods: To examine these associations, we conducted a preregistered analysis of 13,490 participants in the Collaborative Study on the Genetics of Alcoholism. In a structured interview, participants reported their lifetime perpetration of these 3 aggression phenotypes. Results: The data were better fit by a model that treated these aggression phenotypes as 3 distinct latent factors, as compared to models in which the items all loaded onto 1 ("general") or 2 ("substance-related" and "non-substance-related") aggression factors. This 3-factor model fit better for men than women. Subsequent exploratory analyses then showed that among these 3 factors, alcohol-related aggression explained the variance of overall aggression better than the other 2 factors. Conclusions: Our findings suggest that these 3 forms of aggression are distinct phenotypes (especially among men). Yet, people's alcohol-related aggression can accurately characterize their overall aggressive tendencies across these domains. Future research will benefit from articulating the unique and shared pathways and risk factors underlying each of these facets of aggression.en_US
dc.language.isoenen_US
dc.relation.urlhttps://onlinelibrary.wiley.com/doi/10.1111/acer.14412en_US
dc.rights© 2020 by the Research Society on Alcoholism.
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectAggressionen_US
dc.subjectAlcohol Misuseen_US
dc.subjectAlcohol-Related Aggressionen_US
dc.subjectDrug-Related Aggressionen_US
dc.subjectViolenceen_US
dc.titleAlcohol-Related, Drug-Related, and Non-Substance-Related Aggression: 3 Facets of a Single Construct or 3 Distinct Constructs?en_US
dc.typeArticle/Reviewen_US
dc.source.journaltitleAlcoholism, clinical and experimental researchen_US
dc.source.volume44
dc.source.issue9
dc.source.beginpage1852
dc.source.endpage1861
dc.source.countryUnited States
dc.source.countryUnited States
dc.source.countryUnited States
dc.source.countryUnited States
dc.source.countryEngland
dc.description.versionAMen_US
refterms.dateFOA2022-12-05T19:06:48Z
dc.description.institutionSUNY Downstateen_US
dc.description.departmentHenri Begleiter Neurodynamics Laboratoryen_US
dc.description.degreelevelN/Aen_US
dc.identifier.journalAlcoholism, clinical and experimental research


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© 2020 by the Research Society on Alcoholism.
Except where otherwise noted, this item's license is described as © 2020 by the Research Society on Alcoholism.