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dc.contributor.authorStephenson, Mallory
dc.contributor.authorAliev, Fazil
dc.contributor.authorKuo, Sally I-Chun
dc.contributor.authorEdwards, Alexis C.
dc.contributor.authorPandey, Gayathri
dc.contributor.authorSu, Jinni
dc.contributor.authorKamarajan, Chella
dc.contributor.authorDick, Danielle
dc.contributor.authorSalvatore, Jessica E.
dc.date.accessioned2022-11-16T19:58:18Z
dc.date.available2022-11-16T19:58:18Z
dc.date.issued2022-08-12
dc.identifier.citationStephenson M, Aliev F, Kuo SIC, Edwards AC, Pandey G, Su J, Kamarajan C, Dick D, Salvatore JE (2022) The role of adolescent social relationships in promoting alcohol resistance: Interrupting the intergenerational transmission of alcohol misuse. Development and Psychopathology, 1-15; DOI: 10.1017/S0954579422000785.en_US
dc.identifier.issn0954-5794
dc.identifier.eissn1469-2198
dc.identifier.doi10.1017/s0954579422000785
dc.identifier.piiS0954579422000785
dc.identifier.urihttp://hdl.handle.net/20.500.12648/7899
dc.description.abstractGenetic factors contribute to the intergenerational transmission of alcohol misuse, but not all individuals at high genetic risk develop problems. The present study examined adolescent relationships with parents, peers, and romantic partners as predictors of realized resistance, defined as high biological risk for disorder combined with a healthy outcome, to alcohol initiation, heavy episodic drinking, and alcohol use disorder (AUD). Data were from the Collaborative Study on the Genetics of Alcoholism (N = 1,858; 49.9% female; mean age at baseline = 13.91 years). Genetic risk, indexed using family history density and polygenic risk scores for alcohol problems and AUD, was used to define alcohol resistance. Adolescent predictors included parent-child relationship quality, parental monitoring, peer drinking, romantic partner drinking, and social competence. There was little support for the hypothesis that social relationship factors would promote alcohol resistance, with the exception that higher father-child relationship quality was associated with higher resistance to alcohol initiation (βˆ= −0.19, 95% CI = −0.35, −0.03). Unexpectedly, social competence was associated with lower resistance to heavy episodic drinking (βˆ= 0.10, 95% CI = 0.01, 0.20). This pattern of largely null effects underscores how little is known about resistance processes among those at high genetic risk for AUD.en_US
dc.language.isoenen_US
dc.publisherCambridge University Press (CUP)en_US
dc.relation.urlhttps://www.cambridge.org/core/journals/development-and-psychopathology/article/role-of-adolescent-social-relationships-in-promoting-alcohol-resistance-interrupting-the-intergenerational-transmission-of-alcohol-misuse/0FE80C94CF2D15F7793BC497FA5A3C0Aen_US
dc.rights© The Author(s), 2022. Published by Cambridge University Press
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectPsychiatry and Mental healthen_US
dc.subjectDevelopmental and Educational Psychologyen_US
dc.titleThe role of adolescent social relationships in promoting alcohol resistance: Interrupting the intergenerational transmission of alcohol misuseen_US
dc.typeArticle/Reviewen_US
dc.source.journaltitleDevelopment and Psychopathologyen_US
dc.source.beginpage1
dc.source.endpage15
dc.description.versionVoRen_US
refterms.dateFOA2022-11-16T19:58:19Z
dc.description.institutionSUNY Downstateen_US
dc.description.departmentHenri Begleiter Neurodynamics Laboratoryen_US
dc.description.degreelevelN/Aen_US


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© The Author(s), 2022. Published by Cambridge University Press
Except where otherwise noted, this item's license is described as © The Author(s), 2022. Published by Cambridge University Press