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dc.contributor.authorBarr, Peter
dc.contributor.authorSalvatore, Jessica E
dc.contributor.authorMaes, Hermine H
dc.contributor.authorKorhonen, Tellervo
dc.contributor.authorLatvala, Antti
dc.contributor.authorAliev, Fazil
dc.contributor.authorViken, Richard
dc.contributor.authorRose, Richard J
dc.contributor.authorKaprio, Jaakko
dc.contributor.authorDick, Danielle M
dc.date.accessioned2022-10-17T19:15:14Z
dc.date.available2022-10-17T19:15:14Z
dc.identifier.citationBarr PB, Salvatore JE, Maes HH, Korhonen T, Latvala A, Aliev F, Viken R, Rose RJ, Kaprio J, Dick DM. Social Relationships Moderate Genetic Influences on Heavy Drinking in Young Adulthood. J Stud Alcohol Drugs. 2017 Nov;78(6):817-826. doi: 10.15288/jsad.2017.78.817. PMID: 29087815; PMCID: PMC5668991.en_US
dc.identifier.eissn1938-4114
dc.identifier.pmid29087815
dc.identifier.urihttp://hdl.handle.net/20.500.12648/7784
dc.description.abstractObjective: Social relationships, such as committed partnerships, limit risky behaviors like heavy drinking, in part, because of increased social control. The current analyses examine whether involvement in committed relationships or social support extend beyond a main effect to limit genetic liability in heavy drinking (gene-environment interaction) during young adulthood. Method: Using data from the young adult wave of the Finnish Twin Study, FinnTwin12 (n = 3,269), we tested whether involvement in romantic partnerships or social support moderated genetic influences on heavy drinking using biometric twin modeling for gene-environment interaction. Results: Involvement in a romantic partnership was associated with a decline in genetic variance in both males and females, although the overall magnitude of genetic influence was greater in males. Sex differences emerged for social support: increased social support was associated with increased genetic influence for females and reduced genetic influence for males. Conclusions: These findings demonstrate that social relationships are important moderators of genetic influences on young adult alcohol use. Mechanisms of social control that are important in limiting genetic liability during adolescence extend into young adulthood. In addition, although some relationships limit genetic liability equally, others, such as extensive social networks, may operate differently across sex.en_US
dc.language.isoenen_US
dc.relation.urlhttps://www.jsad.com/doi/epdf/10.15288/jsad.2017.78.817en_US
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.titleSocial Relationships Moderate Genetic Influences on Heavy Drinking in Young Adulthood.en_US
dc.typeArticle/Reviewen_US
dc.source.journaltitleJournal of studies on alcohol and drugsen_US
dc.source.volume78
dc.source.issue6
dc.source.beginpage817
dc.source.endpage826
dc.source.countryUnited States
dc.source.countryUnited States
dc.source.countryUnited States
dc.source.countryUnited States
dc.source.countryUnited States
dc.description.versionVoRen_US
refterms.dateFOA2022-10-17T19:15:14Z
dc.description.institutionSUNY Downstateen_US
dc.description.departmentPsychiatry and Behavioral Sciencesen_US
dc.description.degreelevelN/Aen_US
dc.identifier.journalJournal of studies on alcohol and drugs


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