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dc.contributor.authorRose, Richard J
dc.contributor.authorSalvatore, Jessica E
dc.contributor.authorAaltonen, Sari
dc.contributor.authorBarr, Peter
dc.contributor.authorBogl, Leonie H
dc.contributor.authorByers, Holly A
dc.contributor.authorHeikkilä, Kauko
dc.contributor.authorKorhonen, Tellervo
dc.contributor.authorLatvala, Antti
dc.contributor.authorPalviainen, Teemu
dc.contributor.authorRanjit, Anu
dc.contributor.authorWhipp, Alyce M
dc.contributor.authorPulkkinen, Lea
dc.contributor.authorDick, Danielle M
dc.contributor.authorKaprio, Jaakko
dc.date.accessioned2022-10-17T18:43:55Z
dc.date.available2022-10-17T18:43:55Z
dc.date.issued2019-10-23
dc.identifier.citationRose RJ, Salvatore JE, Aaltonen S, Barr PB, Bogl LH, Byers HA, Heikkilä K, Korhonen T, Latvala A, Palviainen T, Ranjit A, Whipp AM, Pulkkinen L, Dick DM, Kaprio J. FinnTwin12 Cohort: An Updated Review. Twin Res Hum Genet. 2019 Oct;22(5):302-311. doi: 10.1017/thg.2019.83. Epub 2019 Oct 23. PMID: 31640839; PMCID: PMC7108792.en_US
dc.identifier.issn1832-4274
dc.identifier.doi10.1017/thg.2019.83
dc.identifier.pmid31640839
dc.identifier.urihttp://hdl.handle.net/20.500.12648/7775
dc.description.abstractThis review offers an update on research conducted with FinnTwin12 (FT12), the youngest of the three Finnish Twin Cohorts. FT12 was designed as a two-stage study. In the first stage, we conducted multiwave questionnaire research enrolling all eligible twins born in Finland during 1983-1987 along with their biological parents. In stage 2, we intensively studied a subset of these twins with in-school assessments at age 12 and semistructured poly-diagnostic interviews at age 14. At baseline, parents of intensively studied twins were administered the adult version of the interview. Laboratory studies with repeat interviews, neuropsychological tests, and collection of DNA were made of intensively studied twins during follow-up in early adulthood. The basic aim of the FT12 study design was to obtain information on individual, familial and school/neighborhood risks for substance use/abuse prior to the onset of regular tobacco and alcohol use and then track trajectories of use and abuse and their consequences into adulthood. But the longitudinal assessments were not narrowly limited to this basic aim, and with multiwave, multirater assessments from ages 11 to 12, the study has created a richly informative data set for analyses of gene-environment interactions of both candidate genes and genomewide measures with measured risk-relevant environments. Because 25 years have elapsed since the start of the study, we are planning a fifth-wave follow-up assessment.en_US
dc.language.isoenen_US
dc.relation.urlhttps://www.cambridge.org/core/journals/twin-research-and-human-genetics/article/finntwin12-cohort-an-updated-review/6B82FC9A6B55F48E848F47917D9794D7en_US
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectLongitudinal twin-family studyen_US
dc.subjectalcoholen_US
dc.subjectdieten_US
dc.subjectdiverse phenotypesen_US
dc.subjectepigeneticsen_US
dc.subjectgeneticsen_US
dc.subjectmental healthen_US
dc.subjectmetabolomicsen_US
dc.subjectphysical activityen_US
dc.subjectsmokingen_US
dc.subjecttwinsen_US
dc.subjecttwo-stage designen_US
dc.titleFinnTwin12 Cohort: An Updated Review.en_US
dc.typeArticle/Reviewen_US
dc.source.journaltitleTwin research and human genetics : the official journal of the International Society for Twin Studiesen_US
dc.source.volume22
dc.source.issue5
dc.source.beginpage302
dc.source.endpage311
dc.source.countryUnited States
dc.source.countryUnited States
dc.source.countryUnited States
dc.source.countryUnited States
dc.source.countryEngland
dc.description.versionVoRen_US
refterms.dateFOA2022-10-17T18:43:55Z
dc.description.institutionSUNY Downstateen_US
dc.description.departmentPsychiatry and Behavioral Sciencesen_US
dc.description.degreelevelN/Aen_US
dc.identifier.journalTwin research and human genetics : the official journal of the International Society for Twin Studies


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Attribution-NonCommercial-NoDerivatives 4.0 International
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