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The Associations of Polygenic Scores for Risky Behaviors and Parenting Behaviors with Adolescent Externalizing Problems.

dc.contributor.authorKsinan, Albert J
dc.contributor.authorSmith, Rebecca L
dc.contributor.authorBarr, Peter
dc.contributor.authorVazsonyi, Alexander T
dc.date.accessioned2022-10-17T17:12:19Z
dc.date.available2022-10-17T17:12:19Z
dc.date.issued2021-07-31
dc.identifier.citationKsinan AJ, Smith RL, Barr PB, Vazsonyi AT. The Associations of Polygenic Scores for Risky Behaviors and Parenting Behaviors with Adolescent Externalizing Problems. Behav Genet. 2022 Jan;52(1):26-37. doi: 10.1007/s10519-021-10079-3. Epub 2021 Jul 31. PMID: 34333687; PMCID: PMC8836487.en_US
dc.identifier.eissn1573-3297
dc.identifier.doi10.1007/s10519-021-10079-3
dc.identifier.pmid34333687
dc.identifier.urihttp://hdl.handle.net/20.500.12648/7765
dc.description.abstractThe current study focused on longitudinal effects of genetics and parental behaviors and their interplay on externalizing behaviors in a panel study following individuals from adolescence to young adulthood. The nationally representative sample of Add Health participants of European ancestry included N = 4142 individuals, measured on three occasions. Parenting was operationalized as experiences with child maltreatment and maternal closeness. Externalizing problems were operationalized as alcohol use, cannabis use, and antisocial behaviors. Genetic effects were operationalized as a polygenic score (PGS) of risky behaviors. The results showed significant effects for child maltreatment, maternal closeness, and PGS, above and beyond other factors and previous levels of externalizing behaviors. Furthermore, maternal closeness was found to negatively correlate with PGS. No significant interaction effects of parenting and PGS were found. The results underscore the joint independent effects of parenting and genetics on the change in externalizing behaviors from adolescence to young adulthood.en_US
dc.language.isoenen_US
dc.relation.urlhttps://link.springer.com/article/10.1007/s10519-021-10079-3en_US
dc.rights© 2021. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectExternalizing behavioren_US
dc.subjectParentingen_US
dc.subjectPolygenic scoreen_US
dc.subjectRisky behaviorsen_US
dc.subjectSubstance useen_US
dc.titleThe Associations of Polygenic Scores for Risky Behaviors and Parenting Behaviors with Adolescent Externalizing Problems.en_US
dc.typeArticle/Reviewen_US
dc.source.journaltitleBehavior geneticsen_US
dc.source.volume52
dc.source.issue1
dc.source.beginpage26
dc.source.endpage37
dc.source.countryUnited States
dc.source.countryUnited States
dc.source.countryUnited States
dc.description.versionAMen_US
refterms.dateFOA2022-10-17T17:12:20Z
dc.description.institutionSUNY Downstateen_US
dc.description.departmentPsychiatry and Behavioral Sciencesen_US
dc.description.degreelevelN/Aen_US
dc.identifier.journalBehavior genetics


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© 2021. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.
Except where otherwise noted, this item's license is described as © 2021. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.