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dc.contributor.authorPerera, Frederica P
dc.contributor.authorLi, Zhigang
dc.contributor.authorWhyatt, Robin
dc.contributor.authorHoepner, Lori
dc.contributor.authorWang, Shuang
dc.contributor.authorCamann, David
dc.contributor.authorRauh, Virginia
dc.date.accessioned2022-10-12T17:54:45Z
dc.date.available2022-10-12T17:54:45Z
dc.date.issued2009-07-20
dc.identifier.citationPerera FP, Li Z, Whyatt R, Hoepner L, Wang S, Camann D, Rauh V. Prenatal airborne polycyclic aromatic hydrocarbon exposure and child IQ at age 5 years. Pediatrics. 2009 Aug;124(2):e195-202. doi: 10.1542/peds.2008-3506. Epub 2009 Jul 20. PMID: 19620194; PMCID: PMC2864932.en_US
dc.identifier.eissn1098-4275
dc.identifier.doi10.1542/peds.2008-3506
dc.identifier.pmid19620194
dc.identifier.urihttp://hdl.handle.net/20.500.12648/7734
dc.description.abstractObjective: This study evaluated the relationship between prenatal exposure to airborne polycyclic aromatic hydrocarbons (PAHs) and child intelligence. Methods: Children of nonsmoking black or Dominican-American women residing in New York City were monitored from in utero to 5 years of age, with determination of prenatal PAH exposure through personal air monitoring for the mothers during pregnancy. At 5 years of age, intelligence was assessed for 249 children by using the Wechsler Preschool and Primary Scale of Intelligence-Revised. Multivariate linear regression models were used to estimate and to test the associations between prenatal PAH exposure and IQ. Results: After adjustment for maternal intelligence, quality of the home caretaking environment, environmental tobacco smoke exposure, and other potentially confounding factors, high PAH levels (above the median of 2.26 ng/m(3)) were inversely associated with full-scale IQ (P = .007) and verbal IQ (P = .003) scores. Children in the high-exposure group had full-scale and verbal IQ scores that were 4.31 and 4.67 points lower, respectively, than those of less-exposed children (<or=2.26 ng/m(3)). The associations between logarithmically transformed, continuous, PAH levels and these IQ measures also were significant (full-scale IQ: beta = -3.00; P = .009; verbal IQ: beta = -3.53; P = .002). Conclusion: These results provide evidence that environmental PAHs at levels encountered in New York City air can affect children's IQ adversely.en_US
dc.language.isoenen_US
dc.relation.urlhttps://publications.aap.org/pediatrics/article-abstract/124/2/e195/72354/Prenatal-Airborne-Polycyclic-Aromatic-Hydrocarbonen_US
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.titlePrenatal airborne polycyclic aromatic hydrocarbon exposure and child IQ at age 5 years.en_US
dc.typeArticle/Reviewen_US
dc.source.journaltitlePediatricsen_US
dc.source.volume124
dc.source.issue2
dc.source.beginpagee195
dc.source.endpage202
dc.source.countryUnited States
dc.source.countryUnited States
dc.source.countryUnited States
dc.source.countryUnited States
dc.source.countryUnited States
dc.source.countryUnited States
dc.source.countryUnited States
dc.source.countryUnited States
dc.source.countryUnited States
dc.source.countryUnited States
dc.source.countryUnited States
dc.source.countryUnited States
dc.source.countryUnited States
dc.source.countryUnited States
dc.source.countryUnited States
dc.source.countryUnited States
dc.source.countryUnited States
dc.source.countryUnited States
dc.description.versionAMen_US
refterms.dateFOA2022-10-12T17:54:46Z
dc.description.institutionSUNY Downstateen_US
dc.description.departmentEnvironmental and Occupational Health Sciencesen_US
dc.description.degreelevelN/Aen_US
dc.identifier.journalPediatrics


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