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dc.contributor.authorPatel, Molini M
dc.contributor.authorHoepner, Lori
dc.contributor.authorGarfinkel, Robin
dc.contributor.authorChillrud, Steven
dc.contributor.authorReyes, Andria
dc.contributor.authorQuinn, James W
dc.contributor.authorPerera, Frederica
dc.contributor.authorMiller, Rachel L
dc.date.accessioned2022-10-12T17:51:03Z
dc.date.available2022-10-12T17:51:03Z
dc.date.issued2009-09-10
dc.identifier.citationPatel MM, Hoepner L, Garfinkel R, Chillrud S, Reyes A, Quinn JW, Perera F, Miller RL. Ambient metals, elemental carbon, and wheeze and cough in New York City children through 24 months of age. Am J Respir Crit Care Med. 2009 Dec 1;180(11):1107-13. doi: 10.1164/rccm.200901-0122OC. Epub 2009 Sep 10. PMID: 19745205; PMCID: PMC2784415.en_US
dc.identifier.eissn1535-4970
dc.identifier.doi10.1164/rccm.200901-0122OC
dc.identifier.pmid19745205
dc.identifier.urihttp://hdl.handle.net/20.500.12648/7733
dc.description.abstractRationale: The effects of exposure to specific components of ambient fine particulate matter (PM(2.5)), including metals and elemental carbon (EC), have not been fully characterized in young children. Objectives: To compare temporal associations among PM(2.5); individual metal constituents of ambient PM(2.5), including nickel (Ni), vanadium (V), and zinc (Zn); and EC and longitudinal reports of respiratory symptoms through 24 months of age. Methods: Study participants were selected from the Columbia Center for Children's Environmental Health birth cohort recruited in New York City between 1998 and 2006. Respiratory symptom data were collected by questionnaire every 3 months through 24 months of age. Ambient pollutant data were obtained from state-operated stationary monitoring sites located within the study area. For each subject, 3-month average inverse-distance weighted concentrations of Ni, V, Zn, EC, and PM(2.5) were calculated for each symptom-reporting period based on the questionnaire date and the preceding 3 months. Associations between pollutants and symptoms were characterized using generalized additive mixed effects models, adjusting for sex, ethnicity, environmental tobacco smoke exposure, and calendar time. Measurements and main results: Increases in ambient Ni and V concentrations were associated significantly with increased probability of wheeze. Increases in EC were associated significantly with cough during the cold/flu season. Total PM(2.5) was not associated with wheeze or cough. Conclusions: These results suggest that exposure to ambient metals and EC from heating oil and/or traffic at levels characteristic of urban environments may be associated with respiratory symptoms among very young children.en_US
dc.language.isoenen_US
dc.relation.urlhttps://www.atsjournals.org/doi/10.1164/rccm.200901-0122OCen_US
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.titleAmbient metals, elemental carbon, and wheeze and cough in New York City children through 24 months of age.en_US
dc.typeArticle/Reviewen_US
dc.source.journaltitleAmerican journal of respiratory and critical care medicineen_US
dc.source.volume180
dc.source.issue11
dc.source.beginpage1107
dc.source.endpage13
dc.source.countryUnited States
dc.source.countryUnited States
dc.source.countryUnited States
dc.source.countryUnited States
dc.source.countryUnited States
dc.source.countryUnited States
dc.source.countryUnited States
dc.source.countryUnited States
dc.source.countryUnited States
dc.source.countryUnited States
dc.source.countryUnited States
dc.source.countryUnited States
dc.source.countryUnited States
dc.description.versionVoRen_US
refterms.dateFOA2022-10-12T17:51:04Z
dc.description.institutionSUNY Downstateen_US
dc.description.departmentEnvironmental and Occupational Health Sciencesen_US
dc.description.degreelevelN/Aen_US
dc.identifier.journalAmerican journal of respiratory and critical care medicine


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