Relationship between maternal demoralization, wheeze, and immunoglobulin E among inner-city children.
dc.contributor.author | Reyes, Marilyn | |
dc.contributor.author | Perzanowski, Matthew S | |
dc.contributor.author | Whyatt, Robin M | |
dc.contributor.author | Kelvin, Elizabeth A | |
dc.contributor.author | Rundle, Andrew G | |
dc.contributor.author | Diaz, Diurka M | |
dc.contributor.author | Hoepner, Lori | |
dc.contributor.author | Perera, Frederica P | |
dc.contributor.author | Rauh, Virginia | |
dc.contributor.author | Miller, Rachel L | |
dc.date.accessioned | 2022-10-11T18:53:46Z | |
dc.date.available | 2022-10-11T18:53:46Z | |
dc.date.issued | 2011-04-14 | |
dc.identifier.citation | Reyes M, Perzanowski MS, Whyatt RM, Kelvin EA, Rundle AG, Diaz DM, Hoepner L, Perera FP, Rauh V, Miller RL. Relationship between maternal demoralization, wheeze, and immunoglobulin E among inner-city children. Ann Allergy Asthma Immunol. 2011 Jul;107(1):42-49.e1. doi: 10.1016/j.anai.2011.03.004. Epub 2011 Apr 14. PMID: 21704884; PMCID: PMC3135280. | en_US |
dc.identifier.eissn | 1534-4436 | |
dc.identifier.doi | 10.1016/j.anai.2011.03.004 | |
dc.identifier.pmid | 21704884 | |
dc.identifier.uri | http://hdl.handle.net/20.500.12648/7722 | |
dc.description.abstract | Background: Prior research has linked maternal prenatal and postnatal mental health with the subsequent development of asthma in children. However, this relationship has not been examined in inner-city African Americans and Hispanics, populations at high risk for asthma. Objective: To determine the relationship of maternal demoralization with wheeze, specific wheeze phenotypes, and seroatopy among children living in a low-income, urban community. Methods: African American and Dominican women aged 18 to 35 years residing in New York City (the Bronx and Northern Manhattan) were recruited during pregnancy (n = 279). Maternal demoralization (ie, psychological distress) was measured both prenatally and postnatally by validated questionnaire. Outcomes included wheeze, transient (birth to 2.5 years of age), late onset (3-5 years), and persistent (birth to 5 years of age), evaluated via questionnaire and total and indoor allergen specific IgE (at birth and ages 2, 3, and 5 years). Logistic regression with generalized estimating equations assessed the association of demoralization with wheeze and atopy. Multinomial regression explored associations between demoralization and specific wheeze phenotypes. Results: Prenatal demoralization significantly predicted overall wheeze (adjusted odds ratio OR, 1.66; 95% confidence interval [CI], 1.29-2.14), transient wheeze (OR, 2.25; 95% CI, 1.34-3.76), and persistent wheeze (OR, 2.69; 95% CI, 1.52-4.77). No association was found between demoralization and IgE after adjustment (total IgE: OR, 1.04; 95% CI, 0.74-1.45; any specific IgE: OR, 0.96; 95% CI, 0.57-1.60). Conclusions: In this inner-city cohort, prenatal demoralization was associated with transient and persistent wheeze. Understanding how maternal demoralization influences children's respiratory health may be important for developing effective interventions among disadvantaged populations. | en_US |
dc.language.iso | en | en_US |
dc.relation.url | https://www.sciencedirect.com/science/article/pii/S1081120611001840 | en_US |
dc.rights | Copyright © 2011 American College of Allergy, Asthma & Immunology. Published by Elsevier Inc. All rights reserved. | |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 International | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.title | Relationship between maternal demoralization, wheeze, and immunoglobulin E among inner-city children. | en_US |
dc.type | Article/Review | en_US |
dc.source.journaltitle | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology | en_US |
dc.source.volume | 107 | |
dc.source.issue | 1 | |
dc.source.beginpage | 42 | |
dc.source.endpage | 49.e1 | |
dc.source.country | United States | |
dc.source.country | United States | |
dc.source.country | United States | |
dc.source.country | United States | |
dc.source.country | United States | |
dc.source.country | United States | |
dc.source.country | United States | |
dc.source.country | United States | |
dc.source.country | United States | |
dc.source.country | United States | |
dc.source.country | United States | |
dc.source.country | United States | |
dc.source.country | United States | |
dc.source.country | United States | |
dc.source.country | United States | |
dc.source.country | United States | |
dc.source.country | United States | |
dc.source.country | United States | |
dc.source.country | United States | |
dc.source.country | United States | |
dc.source.country | United States | |
dc.source.country | United States | |
dc.source.country | United States | |
dc.description.version | VoR | en_US |
refterms.dateFOA | 2022-10-11T18:53:47Z | |
dc.description.institution | SUNY Downstate | en_US |
dc.description.department | Environmental and Occupational Health Sciences | en_US |
dc.description.degreelevel | N/A | en_US |
dc.identifier.journal | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology |