Traffic density and stationary sources of air pollution associated with wheeze, asthma, and immunoglobulin E from birth to age 5 years among New York City children.
Cast your vote
You can rate an item by clicking the amount of stars they wish to award to this item.
When enough users have cast their vote on this item, the average rating will also be shown.
Your vote was cast
Thank you for your feedback
Thank you for your feedback
AuthorPatel, Molini M
Quinn, James W
Jung, Kyung Hwa
Kinney, Patrick L
Perera, Frederica P
Miller, Rachel L
Journal titleEnvironmental research
Publication Begin page1222
Publication End page9
MetadataShow full item record
AbstractExposures to ambient air traffic-related pollutants and their sources have been associated with respiratory and asthma morbidity in children. However, longitudinal investigation of the effects of traffic-related exposures during early childhood is limited. We examined associations of residential proximity and density of traffic and stationary sources of air pollution with wheeze, asthma, and immunoglobulin (Ig) E among New York City children between birth and age 5 years. Subjects included 593 Dominican and African American participants from the Columbia Center for Children's Environmental Health cohort. Prenatally, through age 5 years, residential and respiratory health data were collected every 3-6 months. At ages 2, 3, and 5 years, serum IgE was measured. Spatial data on the proximity and density of roadways and built environment were collected for a 250 m buffer around subjects' homes. Associations of wheeze, asthma, total IgE, and allergen-specific IgE with prenatal, earlier childhood, and concurrent exposures to air pollution sources were analyzed using generalized estimating equations or logistic regression. In repeated measures analyses, concurrent residential density of four-way intersections was associated significantly with wheeze (odds ratio: 1.26; 95% confidence interval [CI]: 1.01, 1.57). Age 1 exposures also were associated with wheeze at subsequent ages. Concurrent proximity to highway was associated more strongly with total IgE (ratio of the geometric mean levels: 1.25; 95% CI: 1.09, 1.42) than were prenatal or earlier childhood exposures. Positive associations also were observed between percent commercial building area and asthma, wheeze, and IgE and between proximity to stationary sources of air pollution and asthma. Longitudinal investigation suggests that among Dominican and African American children living in Northern Manhattan and South Bronx during ages 0-5 years, residence in neighborhoods with high density of traffic and industrial facilities may contribute to chronic respiratory morbidity, and concurrent, prenatal, and earlier childhood exposures may be important. These findings may have broad implications for other urban populations that commonly have high asthma prevalence and exposure to a high density of traffic and stationary air pollution sources.
CitationPatel MM, Quinn JW, Jung KH, Hoepner L, Diaz D, Perzanowski M, Rundle A, Kinney PL, Perera FP, Miller RL. Traffic density and stationary sources of air pollution associated with wheeze, asthma, and immunoglobulin E from birth to age 5 years among New York City children. Environ Res. 2011 Nov;111(8):1222-9. doi: 10.1016/j.envres.2011.08.004. Epub 2011 Aug 19. PMID: 21855059; PMCID: PMC3210909.
The following license files are associated with this item:
- Creative Commons
Except where otherwise noted, this item's license is described as Copyright © 2011 Elsevier Inc. All rights reserved.
- Relationship between maternal demoralization, wheeze, and immunoglobulin E among inner-city children.
- Authors: Reyes M, Perzanowski MS, Whyatt RM, Kelvin EA, Rundle AG, Diaz DM, Hoepner L, Perera FP, Rauh V, Miller RL
- Issue date: 2011 Jul
- Exposure to air pollution and respiratory symptoms during the first 7 years of life in an Italian birth cohort.
- Authors: Ranzi A, Porta D, Badaloni C, Cesaroni G, Lauriola P, Davoli M, Forastiere F
- Issue date: 2014 Jun
- Childhood exposure to fine particulate matter and black carbon and the development of new wheeze between ages 5 and 7 in an urban prospective cohort.
- Authors: Jung KH, Hsu SI, Yan B, Moors K, Chillrud SN, Ross J, Wang S, Perzanowski MS, Kinney PL, Whyatt RM, Perera FP, Miller RL
- Issue date: 2012 Sep 15
- Proximity to Major Roads and Risks of Childhood Recurrent Wheeze and Asthma in a Severe Bronchiolitis Cohort.
- Authors: Freid RD, Qi YS, Espinola JA, Cash RE, Aryan Z, Sullivan AF, Camargo CA Jr
- Issue date: 2021 Apr 15
- Evaluating heterogeneity in indoor and outdoor air pollution using land-use regression and constrained factor analysis.
- Authors: Levy JI, Clougherty JE, Baxter LK, Houseman EA, Paciorek CJ, HEI Health Review Committee
- Issue date: 2010 Dec