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dc.contributor.authorWiden, Elizabeth M
dc.contributor.authorNichols, Amy R
dc.contributor.authorKahn, Linda G
dc.contributor.authorFactor-Litvak, Pam
dc.contributor.authorInsel, Beverly J
dc.contributor.authorHoepner, Lori
dc.contributor.authorDube, Sara M
dc.contributor.authorRauh, Virginia
dc.contributor.authorPerera, Frederica
dc.contributor.authorRundle, Andrew
dc.date.accessioned2022-10-11T15:53:29Z
dc.date.available2022-10-11T15:53:29Z
dc.date.issued2019-12-20
dc.identifier.citationWiden EM, Nichols AR, Kahn LG, Factor-Litvak P, Insel BJ, Hoepner L, Dube SM, Rauh V, Perera F, Rundle A. Prepregnancy obesity is associated with cognitive outcomes in boys in a low-income, multiethnic birth cohort. BMC Pediatr. 2019 Dec 20;19(1):507. doi: 10.1186/s12887-019-1853-4. PMID: 31862007; PMCID: PMC6924019.en_US
dc.identifier.eissn1471-2431
dc.identifier.doi10.1186/s12887-019-1853-4
dc.identifier.pmid31862007
dc.identifier.urihttp://hdl.handle.net/20.500.12648/7691
dc.description.abstractBackground: Maternal obesity and high gestational weight gain (GWG) disproportionally affect low-income populations and may be associated with child neurodevelopment in a sex-specific manner. We examined sex-specific associations between prepregnancy BMI, GWG, and child neurodevelopment at age 7. Methods: Data are from a prospective low-income cohort of African American and Dominican women (n = 368; 44.8% male offspring) enrolled during the second half of pregnancy from 1998 to 2006. Neurodevelopment was measured using the Wechsler Intelligence Scale for Children (WISC-IV) at approximately child age 7. Linear regression estimated associations between prepregnancy BMI, GWG, and child outcomes, adjusting for race/ethnicity, marital status, gestational age at delivery, maternal education, maternal IQ and child age. Results: Overweight affected 23.9% of mothers and obesity affected 22.6%. At age 7, full-scale IQ was higher among girls (99.7 ± 11.6) compared to boys (96.9 ± 13.3). Among boys, but not girls, prepregnancy overweight and obesity were associated with lower full-scale IQ scores [overweight β: - 7.1, 95% CI: (- 12.1, - 2.0); obesity β: - 5.7, 95% CI: (- 10.7, - 0.7)]. GWG was not associated with full-scale IQ in either sex. Conclusions: Prepregnancy overweight and obesity were associated with lower IQ among boys, but not girls, at 7 years. These findings are important considering overweight and obesity prevalence and the long-term implications of early cognitive development.en_US
dc.language.isoenen_US
dc.relation.urlhttps://bmcpediatr.biomedcentral.com/articles/10.1186/s12887-019-1853-4en_US
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectBody mass indexen_US
dc.subjectChilden_US
dc.subjectCognitionen_US
dc.subjectObesityen_US
dc.subjectOverweighten_US
dc.subjectPregnancyen_US
dc.subjectProspective studiesen_US
dc.subjectWechsler scalesen_US
dc.titlePrepregnancy obesity is associated with cognitive outcomes in boys in a low-income, multiethnic birth cohort.en_US
dc.typeArticle/Reviewen_US
dc.source.journaltitleBMC pediatricsen_US
dc.source.volume19
dc.source.issue1
dc.source.beginpage507
dc.source.endpage
dc.source.countryUnited States
dc.source.countryUnited States
dc.source.countryInternational
dc.source.countryInternational
dc.source.countryInternational
dc.source.countryUnited States
dc.source.countryUnited States
dc.source.countryUnited States
dc.source.countryInternational
dc.source.countryUnited States
dc.source.countryUnited States
dc.source.countryEngland
dc.description.versionVoRen_US
refterms.dateFOA2022-10-11T15:53:30Z
dc.description.institutionSUNY Downstateen_US
dc.description.departmentEnvironmental and Occupational Health Sciencesen_US
dc.description.degreelevelN/Aen_US
dc.identifier.journalBMC pediatrics


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