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Genome assembly and geospatial phylogenomics of the bed bug Cimex lectularius.

dc.contributor.authorRosenfeld, Jeffrey A
dc.contributor.authorReeves, Darryl
dc.contributor.authorBrugler, Mercer R
dc.contributor.authorNarechania, Apurva
dc.contributor.authorSimon, Sabrina
dc.contributor.authorDurrett, Russell
dc.contributor.authorFoox, Jonathan
dc.contributor.authorShianna, Kevin
dc.contributor.authorSchatz, Michael C
dc.contributor.authorGandara, Jorge
dc.contributor.authorAfshinnekoo, Ebrahim
dc.contributor.authorLam, Ernest T
dc.contributor.authorHastie, Alex R
dc.contributor.authorChan, Saki
dc.contributor.authorCao, Han
dc.contributor.authorSaghbini, Michael
dc.contributor.authorKentsis, Alex
dc.contributor.authorPlanet, Paul J
dc.contributor.authorKholodovych, Vladyslav
dc.contributor.authorTessler, Michael
dc.contributor.authorBaker, Richard
dc.contributor.authorDeSalle, Rob
dc.contributor.authorSorkin, Louis N
dc.contributor.authorKolokotronis, Sergios-Orestis
dc.contributor.authorSiddall, Mark E
dc.contributor.authorAmato, George
dc.contributor.authorMason, Christopher E
dc.date.accessioned2022-08-25T16:51:55Z
dc.date.available2022-08-25T16:51:55Z
dc.date.issued2016-02-02
dc.identifier.citationRosenfeld JA, Reeves D, Brugler MR, Narechania A, Simon S, Durrett R, Foox J, Shianna K, Schatz MC, Gandara J, Afshinnekoo E, Lam ET, Hastie AR, Chan S, Cao H, Saghbini M, Kentsis A, Planet PJ, Kholodovych V, Tessler M, Baker R, DeSalle R, Sorkin LN, Kolokotronis SO, Siddall ME, Amato G, Mason CE. Genome assembly and geospatial phylogenomics of the bed bug Cimex lectularius. Nat Commun. 2016 Feb 2;7:10164. doi: 10.1038/ncomms10164. PMID: 26836631; PMCID: PMC4740774.en_US
dc.identifier.eissn2041-1723
dc.identifier.doi10.1038/ncomms10164
dc.identifier.pmid26836631
dc.identifier.urihttp://hdl.handle.net/20.500.12648/7500
dc.description.abstractThe common bed bug (Cimex lectularius) has been a persistent pest of humans for thousands of years, yet the genetic basis of the bed bug's basic biology and adaptation to dense human environments is largely unknown. Here we report the assembly, annotation and phylogenetic mapping of the 697.9-Mb Cimex lectularius genome, with an N50 of 971 kb, using both long and short read technologies. A RNA-seq time course across all five developmental stages and male and female adults generated 36,985 coding and noncoding gene models. The most pronounced change in gene expression during the life cycle occurs after feeding on human blood and included genes from the Wolbachia endosymbiont, which shows a simultaneous and coordinated host/commensal response to haematophagous activity. These data provide a rich genetic resource for mapping activity and density of C. lectularius across human hosts and cities, which can help track, manage and control bed bug infestations.en_US
dc.language.isoenen_US
dc.relation.urlhttps://www.nature.com/articles/ncomms10164en_US
dc.rightsAttribution 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.titleGenome assembly and geospatial phylogenomics of the bed bug Cimex lectularius.en_US
dc.typeArticle/Reviewen_US
dc.source.journaltitleNature communicationsen_US
dc.source.volume7
dc.source.beginpage10164
dc.source.endpage
dc.source.countryUnited States
dc.source.countryUnited States
dc.source.countryUnited States
dc.source.countryUnited States
dc.source.countryUnited States
dc.source.countryUnited States
dc.source.countryUnited States
dc.source.countryUnited States
dc.source.countryUnited States
dc.source.countryEngland
dc.description.versionVoRen_US
refterms.dateFOA2022-08-25T16:51:55Z
dc.description.institutionSUNY Downstateen_US
dc.description.departmentEpidemiology and Biostatisticsen_US
dc.description.degreelevelN/Aen_US
dc.identifier.journalNature communications


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Attribution 4.0 International
Except where otherwise noted, this item's license is described as Attribution 4.0 International