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dc.contributor.authorWilen, T E
dc.contributor.authorBiederman, J
dc.contributor.authorPrince, J
dc.contributor.authorspencer, T J
dc.contributor.authorFaraone, Stephen V.
dc.contributor.authorWarburton, R
dc.contributor.authorSchleifer, D
dc.contributor.authorHarding, M
dc.contributor.authorLinehan, C
dc.contributor.authorGeller, D
dc.date.accessioned2021-10-18T15:38:56Z
dc.date.available2021-10-18T15:38:56Z
dc.date.issued1996-09
dc.identifier.issn0002-953X
dc.identifier.eissn1535-7228
dc.identifier.doi10.1176/ajp.153.9.1147
dc.identifier.pii10.1176/ajp.153.9.1147
dc.identifier.urihttp://hdl.handle.net/20.500.12648/6981
dc.description.abstractO bjective: The factor structures of individual positive and negative symptoms as well as global ratings were examined in a diagnostically heterogeneous group of subjects. Method: Subjects were identified through a clinical and family study of patients with major psychoses at a VA medical center and evaluated with the Scale for the Assessment of N egative Symptoms and the Scale for the Assessment of Positive Symptoms. For the examination of global-level factor structures (N =630), both principal-component analysis and factor analysis with orthogonal rotation were used. Factor analysis was used for the examination of item-level factor structures as well (N =549). Results: The principal-component analysis of global ratings revealed three factors: negative symptoms, positive symptoms, and disorganization. The factor analysis of global ratings revealed a negative symptom factor and a positive symptom factor. The itemlevel factor analysis revealed two negative symptom factors (diminished expression and disordered relating), two positive symptom factors (bizarre delusions and auditory hallucinations), and a disorganization factor. Conclusions: The generation of additional meaningful factors at the item level suggests that important information about symptoms is lost when only global ratings are viewed. Future work should explore clinical and pathological correlates of the more differentiated item-level symptom dimensionsen_US
dc.language.isoenen_US
dc.publisherAmerican Psychiatric Association Publishingen_US
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectPsychiatry and Mental healthen_US
dc.titleSix-week, double-blind, placebo-controlled study of desipramine for adult attention deficit hyperactivity disorderen_US
dc.typeArticleen_US
dc.source.journaltitleAmerican Journal of Psychiatryen_US
dc.source.volume153
dc.source.issue9
dc.source.beginpage1147
dc.source.endpage1153
dc.description.versionAMen_US
refterms.dateFOA1997-09-30T00:00:00Z
dc.description.institutionUpstate Medical Universityen_US
dc.description.departmentPsychiatryen_US
dc.description.degreelevelN/Aen_US


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Attribution-NonCommercial-NoDerivatives 4.0 International
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivatives 4.0 International