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dc.contributor.advisorOrtega, Bernardo
dc.contributor.authorCarlson, Christopher
dc.date.accessioned2021-09-08T14:16:46Z
dc.date.available2021-09-08T14:16:46Z
dc.date.issued12/17/2018
dc.identifier.urihttp://hdl.handle.net/20.500.12648/6762
dc.description.abstractUlcerative colitis (UC) is a disease characterized by inflammation of the GI tract, which disturbs the mucosal lining and hinders magnesium (Mg2+) absorption. Research has shown that increasing the dietary intake of Mg2+ decreases the severity of the colitis symptoms, but there is no data on the effect this has on the microbiota of the GI tract or the blood. We found that, in DSS-treated mice, the amount of bacteria in the colon increases with a decrease in dietary Mg2+, and that the concentration of bacteria in the spleen does not correlate to symptom severity or to colonic bacterial amounts. Mg2+ could be used as a supplement for UC patients, treating both hypomagnesemia and lowering colonic bacteria closer to healthy levels.
dc.subjectMagnesium
dc.subjectUlcerative Colitis (UC)
dc.subjectInflammatory Bowel Diseases (IBDs)
dc.subjectBacteria
dc.subjectColon
dc.subjectDietary
dc.titleEffect of Dietary Magnesium Manipulation on the Gastrointestinal Microbiome of a Mouse Model of Ulcerative Colitis
dc.typethesis
refterms.dateFOA2021-09-08T14:16:46Z
dc.description.institutionSUNY Brockport
dc.description.departmentBiology
dc.source.statuspublished
dc.description.publicationtitleSenior Honors Theses
dc.contributor.organizationThe College at Brockport
dc.languate.isoen_US


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