Sickle Cell Anemia

Abstract

What is Sickle Cell Anemia? The purpose of this model is to deepen student understanding of the human body through investigating the structure and function of red blood cells in the human circulatory system. The students will compare and contrast structure and function between normal red blood cells and sickle blood cells and will learn how disruptions in one body system can disrupt homeostasis in other body systems (conditions of stability and determinants of change). Students will engage in mathematics to support their observations and inferences founded within the simulation. Data will be collected to construct linear graphs and build a relation to model the relationship between the number of cells and amount of oxygen transported. This relation will be used to interpret and explain the effects of Sickle Cell Anemia.