• Infographics - Migrating from paper methods to electronic using an enterprise system - Jenzabar EX

      Stam, Kathryn; Thesis Advisor; Lizardi, Ryan; Second Reader; Psarudakis, Robert J. (2021-05)
      SUNY Sullivan has been facing challenges of declining enrollment since the start of the recession in 2008. For the most part the college seems to go through a roller-coaster ride of increasing but steadily declining enrollment spirals ever since. One of our key survival strategies is adaptation to change. Adaptations with programs, delivery methods in the way we offer programs and courses. We tend to be on the cutting edge of technology as it evolves and we adapt to new challenges as long as our funds from SUNY are available. In this paper I will identify some of the gaps in processes that are simply not working. I will look at the theories behind the changes and challenges that are associated with modern adaptations in addition to the reasons why we must change. In this respect I will be looking at our old processes such as paper forms and face to face contact. We are encountering a new world in response to the COVID-19 pandemic. COVID-19 causes all of our in-person activities to be remote. Currently, we are going through our Middle States self-study evaluation. "The Middle States Commission on Higher Education is a voluntary, non-governmental, institutional membership association currently serving higher education institutions in Delaware, the District of Columbia, Maryland, New Jersey, New York, Pennsylvania, Puerto Rico, the Virgin Islands, and any other geographic areas in which the Commission elects to conduct accrediting activities within the United States." (MSCHE, website). Looking at what we do as an institution, we found that we have many "gaps" that need to be filled in. Nothing has proven this more than COVID-19.
    • Information Design and Technology

      Ossowski, Candice (2004-05-01)
      This case study analyzes the effects of transforming a static HTML-based website into a dynamic database-driven one. As part of the study, a small computer company’s static website was redesigned, making it dynamic and database-driven. The theory of Human-Centered Design is applied to a real-world situation and the nine human-centered characteristics are analyzed as they relate to static and dynamic websites
    • Informativeness of Self-Reports of ADHD Symptoms in Monitoring Response to Stimulant Treatment in Clinically Referred Adults With ADHD

      Biederman, Joseph; Fitzgerald, Maura; Spencer, Thomas J.; Adler, Lenard A.; Abrams, Jessica; Biederman, Itai; Faraone, Stephen V. (SAGE Publications, 2018-05-26)
      To investigate the informativeness of self-reports of ADHD symptoms in adults with ADHD in the clinical setting. Method: Subjects were clinically referred adults aged 19 years to 67 years of age of both sexes (N = 54). All subjects were on stable doses of stimulant and were considered responders to treatment. ADHD symptoms were assessed using the ADHD Investigator Symptom Rating Scale (AISRS) and the ADHD Self-Report Scale (ASRS). Spearman’s rank correlations were used to assess the correlations between clinician-assessed ADHD and patients’ self-reports. Results: Spearman’s rank correlation analysis found evidence of a strong, positive association between total scores on the AISRS and the ASRS (rs = .65, df = 52, p < .001). Conclusion: Results have important implications for the management and monitoring of treatment response in the clinical setting through patients’ self-report.(J. of Att. Dis. 2020; 24(3) 420-424)
    • Integrating Information and Communication Tools Effective Strategies for the Classroom

      Phan, Thuc (2013-05-01)
      This project presents effective strategies for integrating information and communication tools (ICTs) within a class. Three major goals that suggest effective implementation of ICTs are, enhancing education by meeting the needs of different learners, facilitating higher levels of learning, and increasing computer literacy skills. Findings from scholarly articles provided a foundation of methods, principles, and strategies in meeting these goals using ICTs. Implementation of integrating ICTs will be shown with an example computer technology course to demonstrate effective strategies. This example course will be used to present effective strategies that are supported by findings from previous research and will include example learning modules located on a learning management system and routine procedures. The content within the example course will revolve around teaching students computer applications though this subject is not relevant towards meeting any goals for effective implementation if integrating ICTs. This is to suggest that another subject, such as science, can be replaced with teaching computer technology. The main focus within this example course should be on the tools, methods, and procedures of teaching and learning with ICTs and how they are used to enhance the learning environment of this course. The ICTs used in meeting the goals of meeting the needs of different learners, facilitating high levels of learning, and increasing computer literacy skills are Schoology.com, Google Docs, Prezi, and Apple Remote Desktop. These ICTs where chosen based on findings from previous research, observation of trending applications, effectiveness of communication and information management, and potential relevance for the future uses.
    • An Inventory Management App in Salesforce

      Chennamaneni, Rahul Madhava Rao; Chiang, Chen-Fu; Adviser; Novillo, Jorge; Reviewer; Rezk, Mohamed, Reviewer (2016-12-01)
      Salesforce is a cloud-based customer relationship management (CRM) software that accelerates business relationships and can transform the working lives of the team. Marc Benioff developed it in the late 1990s and now it has been announced as the world's most innovative company for six consecutive years by Forbes Magazine [1]. Unlike traditional CRM software, Salesforce is an internet service. It is available with just a sign-up and logs in through a browser, and it is immediately available. It is based on cloud computing, where the customers, without the need of installing any traditional software, can access the cloud, i.e., through the internet, for their business needs [2]. Inventory Management (IM) is the method of controlling and supervising the storage, utilization and ordering of components that an organization can track of their items it sells. It is the act of controlling and administering the quantities of products in the sale. For a business, an inventory is the main asset which represents an investment by the owner until the item is sold [3]. To demonstrate its functionalities of Salesforce, I created an application for inventory management. Here, In the inventory management, there are two parts: one is administration part, and another part is customer portal. The administrator manages the inventory and store operations, and the customer buys the products in the inventory through customer portal.
    • Investigating the Role of Paxillin in Mammary Gland Morphogenesis and Breast Cancer Progression

      Turner, Christopher; Xu, Weiyi (2020)
      Breast cancer is one of the most invasive cancers among women. Understanding the mechanisms contributing to breast cancer progression may identify potential ways to prevent and cure the disease. Meanwhile, mammary gland morphogenesis shares similar mechanisms to allow the ducts to invade and occupy the fat pad. Thus, it is equally important to investigate the normal mammary gland development as breast tumor progression. Paxillin, as a focal adhesion scaffold protein, has previously been implicated in multiple types of cancer cell migration and invasion through its role in cell- ECM signaling. Herein, I utilized a novel paxillin conditional knockout mouse model and paxillin knockout mouse crossed with PyMT breast tumor mouse model to show that paxillin is critical for both mammary gland morphogenesis and breast tumor progression. In Chapter 2, by evaluating the developing mammary gland morphology with immunohistochemistry and the three-dimensional cultured mammary organoids and acini, a critical role of paxillin was shown in facilitating apical-basal polarity formation in the luminal epithelial cells in part, through its control of HDAC6 activity and associated microtubule acetylation. Correct polarization and columnar shape of the epithelial cells potentially contributes to lumen formation and branching of the ducts. Investigation in Chapter 3 highlights a crucial role of paxillin in breast cancer invasion and distant organ metastasis, but did not affect the primary tumor growth rate. Further analysis revealed that paxillin is required for the endocytosis and recycling of E- cadherin, which is important for the maintenance of Adherens junction equilibrium during cancer cell collective migration. This thesis characterizes the roles for paxillin in mammary gland morphogenesis and breast cancer progression and reveals the importance of paxillin-dependent apical trafficking in normal epithelial cells, and E-cadherin trafficking in collective migrating tumor cells. Together, this work highlights a trafficking-dependent mechanism for paxillin during both physiologic and pathologic processes in the mammary gland.
    • Investigation of parent-of-origin effects in ADHD candidate genes

      Kim, Jang Woo; Waldman, Irwin D.; Faraone, Stephen V.; Biederman, Joseph; Doyle, Alysa E.; Purcell, Shaun; Arbeitman, Lori; Fagerness, Jesen; Sklar, Pamela; Smoller, Jordan W. (Wiley, 2007)
    • Ipad Application Development For Middle School Science

      LaVere, James (2013-05-01)
      This project was the exploration of researching successful app design and the development of an app prototype for middle school science students. This app prototype is intended to serve needs of middle school science covering the content area of botany, while taking into consideration the affordances of mobile technology to further encourage learning and meaning. The development of the app prototype I am calling “PinBot” was executed in a webbased wireframe tool titled AppShed. The app design, structure and development is based upon the standards set forth by Apple computer inc., app developers and information design theories. This paper chronicles my efforts from concept to final version of app design, with the insight of participant input and scholarly guidance. The application development process enabled me to refine my information in visual, textual and functional forms. The clarity of meaning within the app icons is essential to the user, and the success of the app. Developing and employing the use of video is valued for users with multiple learning styles. The use of video also serves as a means of reinforcing what each tool does and how one can use the app overall. In conclusion, the app development process taught me the balance between communication styles in varied formats and relevance to the individual. The following URL is a direct link to my app prototype: http://appshed.com/appbuilder/preview/193899 The following URL is a direct link to my app prototype video walkthrough: http://www.youtube.com/watch?v=1DO3SQiUcrQ
    • JUNCTIONAL ARMADILLO (β-CATENIN) MAINTAINS PROPER TISSUE ARCHITECTURE DURINGDROSOPHILAEYE DEVELOPMENT

      Pignoni, Francesca; DeSantis, Dana F (2020)
      Formation of thecompoundeye of Drosophilarequires carefully orchestrated developmental events that occur in its progenitor epithelium, the eye imaginal disc.This tissue is composed of two continuous, apposed epithelia: the disc proper epithelium (DpE), which forms the retina, and the peripodial epithelium (PE), which ultimately forms head cuticle. In this work, I describe an armadillo (b-catenin)loss-of-function condition in which the developing DpEis disrupted and displays a phenotype that I call“retinalshift”. This developmental phenotype ultimately results in abnormal fly eye morphology that is incompatible with compound eye vision.I uncover a role for the PE in maintaining proper retinal epithelium morphology during eye formation and trace the molecular mechanism to the regulation of Hippo-Yki pathway in PE cells by the function of Armadillo at the adherens junctions.
    • Knowledge Documentation - From Text to Graphics: Can this improve help desk knowledge transfer?

      Gage, Teresa J. (2007-08-01)
      This thesis was designed to find out if graphics could improve help desk knowledge transfer. Four Web prototype presentation styles were analyzed via the Delphi Method (Michalski 2003) utilizing a panel of experts. The elements tested included the use of text and increasing amounts of graphics presented with different navigation systems. The results proved that graphics could improve knowledge transfer but that a combination of text and graphic may be more effective in a team-centric solution to help desk knowledge transfer.
    • Laboratory-Observed Behavioral Disinhibition in the Young Offspring of Parents With Bipolar Disorder: A High-Risk Pilot Study

      Hirshfeld-Becker, Dina R.; Biederman, Joseph; Henin, Aude; Faraone, Stephen V.; Cayton, Gabrielle A.; Rosenbaum, Jerrold F. (American Psychiatric Association Publishing, 2006-02)
      Objective: This study tested whether behavioral disinhibition is more prevalent among offspring of parents with bipolar disorder than among offspring of parents without bipolar disorder. Method: The authors conducted a secondary analysis of data from a preexisting high-risk study of offspring at risk for panic disorder and depression (N=278) that had included some children with parents who had bipolar disorder (N=34). Children (ages 2–6) had been classified as behaviorally inhibited, disinhibited, or neither in laboratory assessments. Results: Offspring of bipolar parents had significantly higher rates of behavioral disinhibition than offspring of parents without bipolar disorder. Behavioral inhibition did not differ between groups. Differences were not accounted for by parental panic disorder or major depression or by parental history of attention deficit hyperactivity disorder, conduct disorder, antisocial personality, or substance use disorders. Conclusions: Results suggest a familial link between bipolar disorder in parents and behavioral disinhibition in their offspring. Behavioral disinhibition may be a familially transmitted predisposing factor for dysregulatory distress later in life.
    • Lack of Association Between Behavioral Inhibition and Psychosocial Adversity Factors in Children at Risk for Anxiety Disorders

      Hirshfeld-Becker, Dina R.; Biederman, Joseph; Faraone, Stephen V.; Segool, Natasha; Buchwald, Jennifer; Rosenbaum, Jerrold F. (American Psychiatric Association Publishing, 2004-03)
      Objective: In a previous controlled study of offspring at risk for anxiety disorders, the authors found that parental panic disorder with comorbid major depression was associated with child behavioral inhibition, the temperamental tendency to be quiet and restrained in unfamiliar situations. To explore whether this association was mediated by environmental factors, the authors examined associations between psychosocial adversity variables and behavioral inhibition in this group of children. Method: Subjects included 200 offspring of parents with panic disorder and/or major depression and 84 comparison children of parents without mood or anxiety disorders. Behavioral inhibition was assessed through laboratory observations. The associations between behavioral inhibition and the following psychosocial factors were examined: socioeconomic status; an index of adversity factors found in previous studies to be additively associated with child psychopathology; family intactness, conflict, expressiveness, and cohesiveness; exposure to parental psychopathology; sibship size; birth order; and gender. Results: The results showed no associations between behavioral inhibition and any of the psychosocial factors in the study group as a whole, despite adequate power to detect medium effect sizes. Among low-risk comparison children only, some definitions of behavioral inhibition were associated with low socioeconomic status, low family cohesion, and female gender. Conclusions: The results suggest that the psychosocial adversity factors examined in this study do not explain the previous finding that offspring of parents with panic disorder are at high risk for behavioral inhibition.
    • Lack of Association Between Parental Alcohol or Drug Addiction and Behavioral Inhibition in Children

      Biederman, Joseph; Hirshfeld-Becker, Dina R.; Rosenbaum, Jerrold F.; Perenick, Sarah G.; Wood, Julia; Faraone, Stephen V. (American Psychiatric Association Publishing, 2001-10)
      Objective: “Behavioral inhibition to the unfamiliar” has been proposed as a precursor to anxiety. A recent study proposed that it may also be a precursor to alcoholism. The authors sought to replicate the latter finding through a secondary analysis of data from a large study of young children (age 2–6 years)—offspring of parents with panic and depressive disorders—who had been assessed for behavioral inhibition through laboratory-based observations. Method: The offspring were stratified on the basis of presence or absence of parental lifetime history of DSM-III-R alcohol dependence (N=115 versus N=166, respectively) or drug dependence (N=78 versus N=203). The rates of behavioral inhibition were then compared between groups. Results: Despite adequate power to detect associations, neither parental alcohol dependence nor drug dependence was associated with a higher risk for behavioral inhibition in the offspring. Conclusions: These results are not consistent with the hypothesis linking behavioral inhibition to addictions
    • Laminins regulate retinal angiogenesis

      Brunken, William J.; Biswas,Saptarshi (2017)
      Vascular pathologies are the leading causes of acquired blindness in the developed world. While many studies sought to unravel cell-intrinsic and growth factor-mediated regulations of angiogenesis, it is only recently that the role of the basement membrane (BM) components in angiogenesis began to be explored. Several diseases with ocular manifestations are known to alter vascular BM compositions. Therefore, a detailed knowledge of the BM-mediated signals that regulate angiogenesis is of great importance. Laminins, a critical component of the BM, have been shown to regulate several aspects of angiogenesis in the retina. Our laboratory previously demonstrated that the laminin composition of the inner limiting membrane (ILM) regulates astrocyte migration, and consequently vascular expansion along the retinal surface. Here, I examined the role of γ3- and β2-containing laminins in two specific aspects of angiogenesis: 1) vascular branching and endothelial cell proliferation in the nascent vascular plexus, and 2) arterial morphogenesis in the remodeling zone. Results presented in Chapter 2 and Appendix 1 demonstrate that laminin composition of the BM is a critical regulator of microglial recruitment to the growing nascent plexus, where microglia facilitate vascular branching. Furthermore, microglia interact with the astrocyte-derived layer of the vascular BM, and that this interaction regulates iii microglial activation. The activation state of microglia, in turn, regulates endothelial cell proliferation. Results presented in Chapter 3 and Appendix 2 demonstrate that vascular BM laminins are critical regulators of arterial morphogenesis. Specifically, my results reveal a novel mechanism where γ3- containing laminins signal through dystroglycan to induce Dll4/Notch signaling in arterial endothelial cells, regulating proper arterial morphogenesis. Finally, in Appendix 3, I examined the coordinated expression of different laminin chains in the vascular BM. My preliminary results suggest that expressions of laminin α2-, α5- and γ3-chains in the retinal vascular BM are coordinately regulated with the expression of laminin β2-chain. In conclusion, this study sheds light on hitherto unexplored mechanisms by which BM laminins regulate retinal vascular development.
    • Laptop’s In Education – Hype or Help?

      Cronn, Patrick (2006-12-01)
      This study examines the impact of introducing a laptop program for educational teaching in the classroom. By interviewing experts in the field, teachers, administrators, and students at a college level, a phenomenology was completed on the impact of laptops in pedagogy. These ideals were then applied to the Human-Centered Design Theory. “It was not until twenty years ago that serious progress was achieved in applying the available computer and internet technology to support teaching and learning in schools and institutions of higher education. The technology that was previously only available to large corporations and organizations began to be available in homes, schools and universities. This new shift in technology application has provided both students and educators many new advantages and learning possibilities (Altalib, 4).” The numerous ways in which professors and their students interact has always been a critical issue in higher educational institutes. With the increase in technological enhancements over the past several years, study is needed on how collaboration between faculty and students advance.