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dc.contributor.authorTakahashi, Sakae
dc.contributor.authorCui, Yu-hu
dc.contributor.authorKojima, Takuya
dc.contributor.authorHan, Yong-hua
dc.contributor.authorZhou, Ru-lum
dc.contributor.authorKamioka, Masashi
dc.contributor.authorYu, Shun-ying
dc.contributor.authorMatsuura, Masato
dc.contributor.authorMatsushima, Eisuyke
dc.contributor.authorWilcox, Marsha
dc.contributor.authorArinami, Tadao
dc.contributor.authorShen, Yu-cun
dc.contributor.authorFaraone, Stephen V.
dc.contributor.authorTsuang, Ming T.
dc.date.accessioned2021-06-30T14:16:01Z
dc.date.available2021-06-30T14:16:01Z
dc.date.issued2003-06-13
dc.identifier.citationTakahashi, S., Cui, Y.-h., Kojima, T., Han, Y.-h., Zhou, R.-l., Kamioka, M., Yu, S.-y., Matsuura, M., Matsushima, E., Wilcox, M., Arinami, T., Shen, Y.-c., Faraone, S.V. and Tsuang, M.T. (2003), Family-based association study of markers on chromosome 22 in schizophrenia using African-American, European-American, and Chinese families. Am. J. Med. Genet., 120B: 11-17. https://doi.org/10.1002/ajmg.b.20031en_US
dc.identifier.issn0148-7299
dc.identifier.eissn1096-8628
dc.identifier.doi10.1002/ajmg.b.20031
dc.identifier.urihttp://hdl.handle.net/20.500.12648/1791
dc.description.abstractSeveral studies suggest that loci at chromosome 22q11.2-q13 might be linked to susceptibility to schizophrenia. Here we performed family-based association studies on chromosome 22q using 12 DNA microsatellite markers in African-American, European-American, and Chinese pedigrees. The marker D22S683 showed significant linkage and association with schizophrenia in not only the European-American sample but also in a combined sample (European-American and Chinese samples). Notably, D22S683 is located nearby and between D22S278 and D22S283, which have shown linkage and association to schizophrenia in prior reports. However, we found no significant association for the African-American sample. In conclusion, our data provide further support for the idea that the region around D22S683 contains a susceptibility gene for schizophrenia. © 2003 Wiley-Liss, Inc.en_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International*
dc.rights.urihttp://doi.wiley.com/10.1002/tdm_license_1.1
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectGenetics(clinical)en_US
dc.subjectschizophrenia; chromosome 22; D22S683; family-based association study; FBATen_US
dc.titleFamily-based association study of markers on chromosome 22 in schizophrenia using African-American, European-American, and Chinese familiesen_US
dc.typeArticleen_US
dc.source.journaltitleAmerican Journal of Medical Geneticsen_US
dc.source.volume120B
dc.source.issue1
dc.source.beginpage11
dc.source.endpage17
dc.description.versionVoRen_US
refterms.dateFOA2004-06-14T00:00:00Z
dc.description.institutionUpstate Medical Universityen_US
dc.description.departmentPsychiatryen_US
dc.description.degreelevelN/Aen_US


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