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dc.contributor.authorHoogman, Martine
dc.contributor.authorRooij, Daan
dc.contributor.authorKlein, Marieke
dc.contributor.authorBoedhoe, Premika
dc.contributor.authorIlioska, Iva
dc.contributor.authorLi, Ting
dc.contributor.authorPatel, Yash
dc.contributor.authorPostema, Merel C.
dc.contributor.authorZhang‐James, Yanli
dc.contributor.authorAnagnostou, Evdokia
dc.contributor.authorArango, Celso
dc.contributor.authorAuzias, Guillaume
dc.contributor.authorBanaschewski, Tobias
dc.contributor.authorBau, Claiton H. D.
dc.contributor.authorBehrmann, Marlene
dc.contributor.authorBellgrove, Mark A.
dc.contributor.authorBrandeis, Daniel
dc.contributor.authorBrem, Silvia
dc.contributor.authorBusatto, Geraldo F.
dc.contributor.authorCalderoni, Sara
dc.contributor.authorCalvo, Rosa
dc.contributor.authorCastellanos, Francisco X.
dc.contributor.authorCoghill, David
dc.contributor.authorConzelmann, Annette
dc.contributor.authorDaly, Eileen
dc.contributor.authorDeruelle, Christine
dc.contributor.authorDinstein, Ilan
dc.contributor.authorDurston, Sarah
dc.contributor.authorEcker, Christine
dc.contributor.authorEhrlich, Stefan
dc.contributor.authorEpstein, Jeffery N.
dc.contributor.authorFair, Damien A.
dc.contributor.authorFitzgerald, Jacqueline
dc.contributor.authorFreitag, Christine M.
dc.contributor.authorFrodl, Thomas
dc.contributor.authorGallagher, Louise
dc.contributor.authorGrevet, Eugenio H.
dc.contributor.authorHaavik, Jan
dc.contributor.authorHoekstra, Pieter J.
dc.contributor.authorJanssen, Joost
dc.contributor.authorKarkashadze, Georgii
dc.contributor.authorKing, Joseph A.
dc.contributor.authorKonrad, Kerstin
dc.contributor.authorKuntsi, Jonna
dc.contributor.authorLazaro, Luisa
dc.contributor.authorLerch, Jason P.
dc.contributor.authorLesch, Klaus‐Peter
dc.contributor.authorLouza, Mario R.
dc.contributor.authorLuna, Beatriz
dc.contributor.authorMattos, Paulo
dc.contributor.authorMcGrath, Jane
dc.contributor.authorMuratori, Filippo
dc.contributor.authorMurphy, Clodagh
dc.contributor.authorNigg, Joel T.
dc.contributor.authorOberwelland‐Weiss, Eileen
dc.contributor.authorO'Gorman Tuura, Ruth L.
dc.contributor.authorO'Hearn, Kirsten
dc.contributor.authorOosterlaan, Jaap
dc.contributor.authorParellada, Mara
dc.contributor.authorPauli, Paul
dc.contributor.authorPlessen, Kerstin J.
dc.contributor.authorRamos‐Quiroga, J. Antoni
dc.contributor.authorReif, Andreas
dc.contributor.authorReneman, Liesbeth
dc.contributor.authorRetico, Alessandra
dc.contributor.authorRosa, Pedro G. P.
dc.contributor.authorRubia, Katya
dc.contributor.authorShaw, Philip
dc.contributor.authorSilk, Tim J.
dc.contributor.authorTamm, Leanne
dc.contributor.authorVilarroya, Oscar
dc.contributor.authorWalitza, Susanne
dc.contributor.authorJahanshad, Neda
dc.contributor.authorFaraone, Stephen V.
dc.contributor.authorFrancks, Clyde
dc.contributor.authorHeuvel, Odile A.
dc.contributor.authorPaus, Tomas
dc.contributor.authorThompson, Paul M.
dc.contributor.authorBuitelaar, Jan K.
dc.contributor.authorFranke, Barbara
dc.date.accessioned2021-05-17T20:42:42Z
dc.date.available2021-05-17T20:42:42Z
dc.date.issued2020-05-18
dc.identifier.issn1065-9471
dc.identifier.eissn1097-0193
dc.identifier.doi10.1002/hbm.25029
dc.identifier.pii10.1002/hbm.25029
dc.identifier.urihttp://hdl.handle.net/20.500.12648/1719
dc.description.abstractNeuroimaging has been extensively used to study brain structure and function in individuals with attention deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) over the past decades. Two of the main shortcomings of the neuroimaging literature of these disorders are the small sample sizes employed and the heterogeneity of methods used. In 2013 and 2014, the ENIGMA-ADHD and ENIGMA-ASD working groups were respectively, founded with a common goal to address these limitations. Here, we provide a narrative review of the thus far completed and still ongoing projects of these working groups. Due to an implicitly hierarchical psychiatric diagnostic classification system, the fields of ADHD and ASD have developed largely in isolation, despite the considerable overlap in the occurrence of the disorders. The collaboration between the ENIGMA-ADHD and -ASD working groups seeks to bring the neuroimaging efforts of the two disorders closer together. The outcomes of case–control studies of subcortical and cortical structures showed that subcortical volumes are similarly affected in ASD and ADHD, albeit with small effect sizes. Cortical analyses identified unique differences in each disorder, but also considerable overlap between the two, specifically in cortical thickness. Ongoing work is examining alternative research questions, such as brain laterality, prediction of case–control status, and anatomical heterogeneity. In brief, great strides have been made toward fulfilling the aims of the ENIGMA collaborations, while new ideas and follow-up analyses continue that include more imaging modalities (diffusion MRI and resting-state functional MRI), collaborations with other large databases, and samples with dual diagnoses.en_US
dc.description.sponsorshipNational Institute of Mental Healthen_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectAnatomyen_US
dc.subjectRadiological and Ultrasound Technologyen_US
dc.subjectRadiology Nuclear Medicine and imagingen_US
dc.subjectNeurologyen_US
dc.subjectClinical Neurologyen_US
dc.titleConsortium neuroscience of attention deficit/hyperactivity disorder and autism spectrum disorder: The ENIGMA adventureen_US
dc.typeArticleen_US
dc.source.journaltitleHuman Brain Mappingen_US
dc.description.versionVoRen_US
refterms.dateFOA2021-05-17T20:42:42Z
dc.description.institutionUpstate Medical Universityen_US
dc.description.departmentPsychiatryen_US
dc.description.degreelevelN/Aen_US


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Attribution-NonCommercial-NoDerivatives 4.0 International
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivatives 4.0 International