Associations of Work Hours, Job Strain, and Occupation With Endothelial Function
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Author
Charles, Luenda E.Fekedulegn, Desta
Landsbergis, Paul
Burchfiel, Cecil M.
Baron, Sherry
Kaufman, Joel D.
Stukovsky, Karen Hinckley
Fujishiro, Kaori
Foy, Capri G.
Andrew, Michael E.
Diez Roux, Ana V.
Journal title
Journal of Occupational & Environmental MedicineDate Published
2014-11Publication Volume
56Publication Issue
11Publication Begin page
1153Publication End page
1160
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Show full item recordAbstract
Objective: To investigate associations of work hours, job control, job demands, job strain, and occupational category with brachial artery flow-mediated dilation (FMD) in 1499 Multi-Ethnic Study of Atherosclerosis participants. Methods: Flow-mediated dilation was obtained using high-resolution ultrasound. Mean values of FMD were examined across categories of occupation, work hours, and the other exposures using regression analyses. Results: Occupational category was significantly associated with FMD overall, with blue-collar workers showing the lowest mean values-management/professional = 4.97 ± 0.22%; sales/office = 5.19 ± 0.28%; services = 4.73 ± 0.29%; and blue-collar workers = 4.01 ± 0.26% (adjusted P < 0.001). There was evidence of effect modification by sex (interaction P = 0.031)-significant associations were observed among women (adjusted P = 0.002) and nearly significant results among men (adjusted P = 0.087). Other exposures were not significantly associated with FMD. Conclusions: Differences in endothelial function may account for some of the variation in cardiovascular disease across occupational groups.Citation
Charles LE, Fekedulegn D, Landsbergis P, Burchfiel CM, Baron S, Kaufman JD, Stukovsky KH, Fujishiro K, Foy CG, Andrew ME, Diez Roux AV. Associations of work hours, job strain, and occupation with endothelial function: the Multi-Ethnic Study of Atherosclerosis (MESA). J Occup Environ Med. 2014 Nov;56(11):1153-60. doi: 10.1097/JOM.0000000000000311. PMID: 25376409; PMCID: PMC4225634.DOI
10.1097/jom.0000000000000311ae974a485f413a2113503eed53cd6c53
10.1097/jom.0000000000000311
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- Creative Commons
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivatives 4.0 International
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