Background rates of all-cause mortality, hospitalizations, and emergency department visits among nursing home residents in Ontario, Canada to inform COVID-19 vaccine safety assessments
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Author
Sundaram, MariaNasreen, Sharifa
Calzavara, Andrew
He, Siyi
Chung, Hannah
Bronskill, Susan E.
Buchan, Sarah A.
Tadrous, Mina
Tanuseputro, Peter
Wilson, Kumanan
Wilson, Sarah
Kwong, Jeffrey C.
Journal title
VaccineDate Published
2021-08Publication Volume
39Publication Issue
37Publication Begin page
5265Publication End page
5270
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Show full item recordAbstract
Background: Nursing home (NH) residents are prioritized for COVID-19 vaccination. We report monthly mortality, hospitalizations, and emergency department (ED) visit incidence rates (IRs) during 2010-2020 to provide context for COVID-19 vaccine safety assessments. Methods: We observed outcomes among all NH residents in Ontario using administrative databases. IRs were calculated by month, sex, and age group. Comparisons between months were assessed using one-sample t-tests; comparisons by age and sex were assessed using chi-squared tests. Results: From 2010 to 2019, there were 83,453 (SD: 652.4) NH residents per month, with an average of 2.3 (SD: 0.28) deaths, 3.1 (SD: 0.16) hospitalizations, and 3.6 (SD: 0.17) ED visits per 100 residents per month. From March to December 2020, mortality IRs were increased, but hospitalization and ED visit IRs were reduced (p < 0.05). Conclusion: We identified consistent monthly mortality, hospitalization, and ED visit IRs during 2010-2019. Marked differences in these rates were observed during 2020, coinciding with the COVID-19 pandemic.Citation
Sundaram M, Nasreen S, Calzavara A, He S, Chung H, Bronskill SE, Buchan SA, Tadrous M, Tanuseputro P, Wilson K, Wilson S, Kwong JC; Canadian Immunization Research Network (CIRN) investigators. Background rates of all-cause mortality, hospitalizations, and emergency department visits among nursing home residents in Ontario, Canada to inform COVID-19 vaccine safety assessments. Vaccine. 2021 Aug 31;39(37):5265-5270. doi: 10.1016/j.vaccine.2021.07.060. Epub 2021 Jul 23. PMID: 34373124; PMCID: PMC8299226.DOI
10.1016/j.vaccine.2021.07.060ae974a485f413a2113503eed53cd6c53
10.1016/j.vaccine.2021.07.060
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