Understanding CFH and C Protein Interactions by Surface Plasmon Resonance

David Menzies; Julia R. Koeppe

Name:

Quest2023_21.pdf

Size:

373.8Kb

Format:

PDF

Download

Cast your vote
You can rate an item by clicking the amount of stars they wish to award to this item. When enough users have cast their vote on this item, the average rating will also be shown.

Star rating

Your vote was cast
Thank you for your feedback

Author

David Menzies
Julia R. Koeppe

Date Published

2023

Metadata

Show full item record

URI

http://hdl.handle.net/20.500.12648/14871

Abstract

Complement Factor H (CFH) and complement component (C ) are proteins responsible for helping the innate immune system to respond to pathogen clearance in the body and when misregulated can lead to autoimmune disorders. CFH is considered to be a possible regulator protein in this system whereas C activation is an essential step in the system&# ;s response. Surface Plasmon Resonance (SPR) was used to study the interactions between the two components allowing for the binding kinetics to be observed.

Collections

Quest