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Chlamydia pneumoniae immunoglobulin E antibody levels in patients with asthma compared with non-asthma

dc.contributor.authorSmith-Norowitz, Tamar A
dc.contributor.authorLoeffler, Jeffrey
dc.contributor.authorHuang, Yvonne
dc.contributor.authorKlein, Elliot
dc.contributor.authorNorowitz, Yitzchok M
dc.contributor.authorHammerschlag, Margaret R
dc.contributor.authorJoks, Rauno
dc.contributor.authorKohlhoff, Stephan
dc.date.accessioned2023-07-07T17:08:40Z
dc.date.available2023-07-07T17:08:40Z
dc.date.issued2020-02-29
dc.identifier.citationSmith-Norowitz TA, Loeffler J, Huang Y, Klein E, Norowitz YM, Hammerschlag MR, Joks R, Kohlhoff S. Chlamydia pneumoniae immunoglobulin E antibody levels in patients with asthma compared with non-asthma. Heliyon. 2020 Feb 29;6(2):e03512. doi: 10.1016/j.heliyon.2020.e03512. PMID: 32140608; PMCID: PMC7052057.en_US
dc.identifier.issn2405-8440
dc.identifier.doi10.1016/j.heliyon.2020.e03512
dc.identifier.pmid32140608
dc.identifier.urihttp://hdl.handle.net/20.500.12648/10412
dc.description.abstractis an obligate intracellular bacterium that causes respiratory infection in adults and children. There is evidence for an association between atypical bacterial pathogens and asthma pathogenesis. We sought to determine whether past infection triggers - IgE antibodies (Abs) in asthmatics and non-asthmatics, who had detectable IgG titers. IgE Abs were quantified using enzyme immunoassay (EIA). IgE Ab levels were higher in asthmatics compared with non-asthmatics. There was no correlation found between total serum IgE levels and specific IgE Ab levels. infection may trigger IgE-specific responses in asthmatics.
dc.language.isoenen_US
dc.relation.urlhttps://www.cell.com/heliyon/fulltext/S2405-8440(20)30357-1en_US
dc.rights© 2020 Published by Elsevier Ltd.
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectAsthmaen_US
dc.subjectBiological sciencesen_US
dc.subjectChlamydia pneumoniaeen_US
dc.subjectHealth sciencesen_US
dc.subjectImmunoglobulin Een_US
dc.subjectImmunologyen_US
dc.subjectInfectious diseaseen_US
dc.titleChlamydia pneumoniae immunoglobulin E antibody levels in patients with asthma compared with non-asthmaen_US
dc.typeArticle/Reviewen_US
dc.source.journaltitleHeliyonen_US
dc.source.volume6
dc.source.issue2
dc.source.beginpagee03512
dc.source.endpage
dc.source.countryEngland
dc.description.versionVoRen_US
refterms.dateFOA2023-07-07T17:08:40Z
html.description.abstractis an obligate intracellular bacterium that causes respiratory infection in adults and children. There is evidence for an association between atypical bacterial pathogens and asthma pathogenesis. We sought to determine whether past infection triggers - IgE antibodies (Abs) in asthmatics and non-asthmatics, who had detectable IgG titers. IgE Abs were quantified using enzyme immunoassay (EIA). IgE Ab levels were higher in asthmatics compared with non-asthmatics. There was no correlation found between total serum IgE levels and specific IgE Ab levels. infection may trigger IgE-specific responses in asthmatics.
dc.description.institutionSUNY Downstateen_US
dc.description.departmentPediatricsen_US
dc.description.degreelevelN/Aen_US
dc.identifier.journalHeliyon
dc.identifier.issue2en_US


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© 2020 Published by Elsevier Ltd.
Except where otherwise noted, this item's license is described as © 2020 Published by Elsevier Ltd.