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Genetic and culture-based approaches for detecting macrolide resistance in Chlamydia pneumoniae.

dc.contributor.authorRiska, Paul F
dc.contributor.authorKutlin, Andrei
dc.contributor.authorAjiboye, Patrick
dc.contributor.authorCua, Arnold
dc.contributor.authorRoblin, Patricia M
dc.contributor.authorHammerschlag, Margaret R
dc.date.accessioned2023-07-05T16:14:30Z
dc.date.available2023-07-05T16:14:30Z
dc.date.issued2004-09
dc.identifier.citationRiska PF, Kutlin A, Ajiboye P, Cua A, Roblin PM, Hammerschlag MR. Genetic and culture-based approaches for detecting macrolide resistance in Chlamydia pneumoniae. Antimicrob Agents Chemother. 2004 Sep;48(9):3586-90. doi: 10.1128/AAC.48.9.3586-3590.2004. PMID: 15328134; PMCID: PMC514725.en_US
dc.identifier.issn0066-4804
dc.identifier.pmid15328134
dc.identifier.urihttp://hdl.handle.net/20.500.12648/10368
dc.description.abstractThree clinical Chlamydia pneumoniae isolates for which the MIC of azithromycin increased after treatment were investigated for genetic evidence of macrolide resistance. Attempts to induce antibiotic resistance in vitro were made. No genetic mechanism was identified for the phenotypic change in these C. pneumoniae isolates. No macrolide resistance was obtained in vitro.
dc.language.isoenen_US
dc.relation.urlhttps://journals.asm.org/doi/epub/10.1128/aac.48.9.3586-3590.2004en_US
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.titleGenetic and culture-based approaches for detecting macrolide resistance in Chlamydia pneumoniae.en_US
dc.typeArticle/Reviewen_US
dc.source.journaltitleAntimicrobial agents and chemotherapyen_US
dc.source.volume48
dc.source.issue9
dc.source.beginpage3586
dc.source.endpage90
dc.source.countryUnited States
dc.source.countryUnited States
dc.description.versionVoRen_US
refterms.dateFOA2023-07-05T16:14:30Z
html.description.abstractThree clinical Chlamydia pneumoniae isolates for which the MIC of azithromycin increased after treatment were investigated for genetic evidence of macrolide resistance. Attempts to induce antibiotic resistance in vitro were made. No genetic mechanism was identified for the phenotypic change in these C. pneumoniae isolates. No macrolide resistance was obtained in vitro.
dc.description.institutionN/Aen_US
dc.description.departmentPediatricsen_US
dc.description.degreelevelN/Aen_US
dc.identifier.journalAntimicrobial agents and chemotherapy
dc.identifier.issue9en_US


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