Ultrastructural study of Chlamydia pneumoniae in a continuous-infection model.

Kutlin, A; Flegg, C; Stenzel, D; Reznik, T; Roblin, P M; Mathews, S; Timms, P; Hammerschlag, M R

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Author

Kutlin, A
Flegg, C
Stenzel, D
Reznik, T
Roblin, P M
Mathews, S
Timms, P
Hammerschlag, M R

Journal title

Journal of clinical microbiology

Date Published

2001-10

Publication Volume

Publication Issue

Publication Begin page

3721

Publication End page

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URI

http://hdl.handle.net/20.500.12648/10356

Abstract

We have established an in vitro model of long-term continuous Chlamydia pneumoniae infection in HEp-2 cells. Using transmission electron microscopy, we demonstrated the presence of spontaneous abnormal chlamydial inclusions similar in appearance to the persistent chlamydial forms induced in vitro by treatment with cytokines or antibiotics or by nutrient deprivation.

Citation

Kutlin A, Flegg C, Stenzel D, Reznik T, Roblin PM, Mathews S, Timms P, Hammerschlag MR. Ultrastructural study of Chlamydia pneumoniae in a continuous-infection model. J Clin Microbiol. 2001 Oct;39(10):3721-3. doi: 10.1128/JCM.39.10.3721-3723.2001. PMID: 11574601; PMCID: PMC88417.

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Downstate College of Medicine

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