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dc.contributor.authorHammerschlag, Margaret R.
dc.date.accessioned2023-06-30T16:21:39Z
dc.date.available2023-06-30T16:21:39Z
dc.date.issued1996
dc.identifier.citationHammerschlag MR. Diagnostic methods for intracellular pathogens. Clin Microbiol Infect. 1996 Mar;1 Suppl 1:S3-S8. doi: 10.1111/j.1469-0691.1996.tb00582.x. PMID: 11866786.en_US
dc.identifier.eissn1469-0691
dc.identifier.pmid11866786
dc.identifier.urihttp://hdl.handle.net/20.500.12648/10338
dc.description.abstractDiagnosis of infection with Chlamydia pneumoniae is difficult and the optimal diagnostic procedure has yet to be established. C. pneumoniae is more difficult to isolate in tissue culture than C. trachomatis. Attention must be paid to the site from which the specimen is taken, and all specimens should be processed within 24 h or stored at 4 C. Serologic diagnosis largely depends on microimmunofluorescence testing which, despite proposed criteria, still has a large subjective component. Serology has limitations in terms of both sensitivity and specificity and antibodies may be difficult to detect in individuals with positive C. pneumoniae cultures. Non-culture methods include enzyme immunoassays, fluorescent-antibody techniques and DNA probes. The most promising appears to be PCR. Co-infection of C. pneumoniae and other respiratory organisms seem to be common.
dc.language.isoenen_US
dc.relation.urlhttps://www.clinicalmicrobiologyandinfection.com/article/S1198-743X(14)65224-1/fulltexten_US
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.titleDiagnostic methods for intracellular pathogens.en_US
dc.typeArticle/Reviewen_US
dc.source.journaltitleClinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseasesen_US
dc.source.volume1 Suppl 1
dc.source.beginpageS3
dc.source.endpageS8
dc.source.countryEngland
dc.description.versionVoRen_US
refterms.dateFOA2023-06-30T16:21:41Z
html.description.abstractDiagnosis of infection with Chlamydia pneumoniae is difficult and the optimal diagnostic procedure has yet to be established. C. pneumoniae is more difficult to isolate in tissue culture than C. trachomatis. Attention must be paid to the site from which the specimen is taken, and all specimens should be processed within 24 h or stored at 4 C. Serologic diagnosis largely depends on microimmunofluorescence testing which, despite proposed criteria, still has a large subjective component. Serology has limitations in terms of both sensitivity and specificity and antibodies may be difficult to detect in individuals with positive C. pneumoniae cultures. Non-culture methods include enzyme immunoassays, fluorescent-antibody techniques and DNA probes. The most promising appears to be PCR. Co-infection of C. pneumoniae and other respiratory organisms seem to be common.
dc.description.institutionSUNY Downstateen_US
dc.description.departmentPediatricsen_US
dc.description.degreelevelN/Aen_US
dc.identifier.journalClinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases


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