Comparison of a chemiluminometric immunoassay with culture for diagnosis of chlamydial infections in infants.
Cast your vote
You can rate an item by clicking the amount of stars they wish to award to this item.
When enough users have cast their vote on this item, the average rating will also be shown.
Your vote was cast
Thank you for your feedback
Thank you for your feedback
Journal titleJournal of clinical microbiology
Publication Begin page1867
Publication End page9
MetadataShow full item record
AbstractThe performance of Magic Lite (CIBA-Corning), a chemiluminescent immunoassay (CIA), was compared with that of culture for the diagnosis of neonatal chlamydial conjunctivitis and respiratory infection. We performed a retrospective evaluation of 51 ocular and 96 nasopharyngeal specimens previously collected for culture testing with the CIA. The sensitivities for the ocular and the nasopharyngeal specimens were 91 and 91.7%, respectively. The specificities for both sites were 100%. A subsequent prospective study evaluating 71 ocular and 38 nasopharyngeal specimens revealed sensitivities of 83.3 and 20%, respectively. The specificities for both sites were 100%. The CIA performed favorably, compared with culture, for the diagnosis of chlamydial conjunctivitis; however, the CIA appeared less sensitive for the diagnosis of respiratory infection, including pneumonia.
CitationDumornay W, Roblin PM, Gelling M, Hammerschlag MR, Worku M. Comparison of a chemiluminometric immunoassay with culture for diagnosis of chlamydial infections in infants. J Clin Microbiol. 1992 Jul;30(7):1867-9. doi: 10.1128/jcm.30.7.1867-1869.1992. PMID: 1629345; PMCID: PMC265395.
The following license files are associated with this item:
- Creative Commons
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivatives 4.0 International
- Evaluation of a new optical immunoassay for diagnosis of neonatal chlamydial conjunctivitis.
- Authors: Roblin PM, Gelling M, Kutlin A, Tsumura N, Hammerschlag MR
- Issue date: 1997 Feb
- Effects of broadening the gold standard on the performance of a chemiluminometric immunoassay to detect Chlamydia trachomatis antigens in centrifuged first void urine and urethral swab samples from men.
- Authors: Jang D, Sellors JW, Mahony JB, Pickard L, Chernesky MA
- Issue date: 1992 Nov-Dec
- Comparison of enzyme immunoassay and culture for diagnosis of chlamydial conjunctivitis and respiratory infections in infants.
- Authors: Hammerschlag MR, Roblin PM, Cummings C, Williams TH, Worku M, Howard LV
- Issue date: 1987 Dec
- Use of polymerase chain reaction for the detection of Chlamydia trachomatis in ocular and nasopharyngeal specimens from infants with conjunctivitis.
- Authors: Hammerschlag MR, Roblin PM, Gelling M, Tsumura N, Jule JE, Kutlin A
- Issue date: 1997 Mar
- Comparison of two enzyme immunoassays to culture for the diagnosis of chlamydial conjunctivitis and respiratory infections in infants.
- Authors: Hammerschlag MR, Roblin PM, Gelling M, Worku M
- Issue date: 1990 Aug