In vitro activities of five quinolones against Chlamydia pneumoniae.

Hammerschlag, M R; Hyman, C L; Roblin, P M

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Author

Hammerschlag, M R
Hyman, C L
Roblin, P M

Journal title

Antimicrobial agents and chemotherapy

Date Published

1992-03

Publication Volume

Publication Issue

Publication Begin page

682

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URI

http://hdl.handle.net/20.500.12648/10322

Abstract

The in vitro susceptibilities of 10 strains of Chlamydia pneumoniae were determined for five quinolones, including ciprofloxacin, ofloxacin, fleroxacin, temafloxacin, and sparfloxacin. Sparfloxacin was the most active compound tested, followed by ofloxacin and temafloxacin. Ciprofloxacin and fleroxacin were the least active. The use of HEp-2 cells for testing C. pneumoniae resulted in larger inclusions but essentially the same endpoints as were seen with use of HeLa 229 cells.

Citation

Hammerschlag MR, Hyman CL, Roblin PM. In vitro activities of five quinolones against Chlamydia pneumoniae. Antimicrob Agents Chemother. 1992 Mar;36(3):682-3. doi: 10.1128/AAC.36.3.682. PMID: 1320366; PMCID: PMC190581.

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Downstate College of Medicine

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