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Journal Title
Clinical practice and cases in emergency medicine
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Publication Date
2017-01-23
Type
Book Title
Publication Volume
1
Publication Issue
1
Publication Begin
9
Publication End
12
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cpcem-01-09.pdf
Adobe PDF, 951.6 KB
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Abstract
Torsades de Pointes (TdP) is a polymorphic ventricular tachycardia that occurs in the presence of an acquired or congenital long QT syndrome (LQTS). We present the case of a 57 year-old man with end-stage renal disease on methadone maintenance in which there occurred multiple episodes of TdP during sleep. The patient was found to have a QTc interval of 548 milliseconds, and the dysrhythmia was successfully treated with isoproterenol infusion and methadone substitution. It is surmised that the patient had a multifactorial, acquired LQTS that during somnolence, reached a critical threshold of QT prolongation to lead to the development of TdP.
Citation
Carmelli G, deSouza IS. Sleep-Associated Torsades de Pointes: A Case Report. Clin Pract Cases Emerg Med. 2017 Jan 23;1(1):9-12. doi: 10.5811/cpcem.2016.10.31352. PMID: 29849392; PMCID: PMC5965430.