Ultrastructural study of Chlamydia pneumoniae in a continuous-infection model.

Kutlin, A; Flegg, C; Stenzel, D; Reznik, T; Roblin, P M; Mathews, S; Timms, P; Hammerschlag, M R

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Ultrastructural study of Chlamydia pneumoniae in a continuous-infection model.

Kutlin, A; Flegg, C; Stenzel, D; Reznik, T; Roblin, P M; Mathews, S; Timms, P; Hammerschlag, M R

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Journal of clinical microbiology

Publication Date

2001-10

Publication Volume

39

Publication Issue

10

Publication Begin

3721

Publication End

3

Abstract

We have established an in vitro model of long-term continuous Chlamydia pneumoniae infection in HEp-2 cells. Using transmission electron microscopy, we demonstrated the presence of spontaneous abnormal chlamydial inclusions similar in appearance to the persistent chlamydial forms induced in vitro by treatment with cytokines or antibiotics or by nutrient deprivation.

Citation

Kutlin A, Flegg C, Stenzel D, Reznik T, Roblin PM, Mathews S, Timms P, Hammerschlag MR. Ultrastructural study of Chlamydia pneumoniae in a continuous-infection model. J Clin Microbiol. 2001 Oct;39(10):3721-3. doi: 10.1128/JCM.39.10.3721-3723.2001. PMID: 11574601; PMCID: PMC88417.

Ultrastructural study of Chlamydia pneumoniae in a continuous-infection model.

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