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Generation of Dictyostelium discoideum Cells Lacking Adhesion Proteins Talin A and B Using CRISPR/Cas9
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Artemenko, Yulia
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2025
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Quest2025_028.pdf
Adobe PDF, 3.52 MB
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Dictyostelium discoideum is a common model organism used to study migration. Shear flow can be used as a signal to guide cell migration, although the mechanism is poorly understood. To determine the role of cell adhesion in this process, we are generating knockouts of adhesion mediator, Talin, using CRISPR/Cas9.