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Alcohol Misuse Across the Lifespan: Insights from Developmental Studies in Behavior Genetics.
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Policy insights from the behavioral and brain sciences
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Publication Date
2017-08-24
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4
Publication Issue
2
Publication Begin
186
Publication End
193
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nihms916794.pdf
Adobe PDF, 76.26 KB
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Abstract
Alcohol misuse, one of today's greatest public health challenges, is a developmentally dynamic, complex behavior at the intersection of genetic and environmental influences. This review examines such influences from a behavior genetics perspective and discusses implications for public policy. Alcohol misuse is moderately heritable with genetic influences accounting for around 50% of its variance, but to date few specific genes have been identified. However, numerous environmental and social factors moderate genetic risk, including parents, peers, romantic partners, family dynamics, employment, laws, and cultural influences. These moderating factors change in salience across development, and, accordingly, no one-size-fits-all approach is suitable for reducing alcohol misuse at a large scale. We provide examples of some effective prevention and intervention programs and discuss a framework for using the behavior genetics evidence to inform future public policy efforts.
Citation
Savage JE, Long EC, Kuo SI, Cooke ME, Su J, Barr PB, Salvatore JE. Alcohol Misuse Across the Lifespan: Insights from Developmental Studies in Behavior Genetics. Policy Insights Behav Brain Sci. 2017;4(2):186-193. doi: 10.1177/2372732217720222. Epub 2017 Aug 24. PMID: 29430518; PMCID: PMC5802413.