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Heavy Metal on the Brain: CeruloplasminTess

Alecksynas, Tess
; 
Townsend, Eric
; 
Zhu, Angela
; 
Brabetz, Barbara
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Ceruloplasmin
 Iron in the body
 Brain—Localization of functions
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2016
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Student Research Showcase - April 4th, 2016
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https://hdl.handle.net/20.500.12648/83400
Abstract
The absence of functional ceruloplasminferroxidase activity impairs the body’s ability to export iron out of its tissues. The resulting accumulation of iron in the cells result in tissue damage and ultimately health concerns such as aceruloplasminaemia, Parkinsonism, and multiple system atrophy (Miyajima, 2003) (Motta, 2009).While not directly affected by mutations in the CP gene, individuals with copper-transport diseases such as Wilson disease and Menkes’diseasemay exhibit low levels of Ceruloplasmin (Mercer, 2001).
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