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Prostatic irradiation-induced sexual dysfunction: A review and multidisciplinary guide to management in the radical radiotherapy era (Part II on Urological Management)
Journal Title
Reports of Practical Oncology & Radiotherapy
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Publication Date
2020-07
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Publication Volume
25
Publication Issue
4
Publication Begin
619
Publication End
624
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Abstract
Prostate cancer is the most common malignancy in men and the second leading cause of cancer-related death in men. Radiotherapy is a curative option that is administered via external beam radiation, brachytherapy, or in combination. Sexual dysfunction is a common toxicity following radiotherapy, similar to men undergoing radical prostatectomy, but the etiology is different. The pathophysiology of radiation-induced sexual dysfunction is multi-factorial, and the toxicity is a major cause of impaired quality of life among long-term prostate cancer survivors. Management of a patient's sexual function during and after radiotherapy requires multidisciplinary coordination of care between radiation oncology, urology, psychiatry, pharmacy, and dermatology. This review provides a framework for clinicians to better understand prostatic radiotherapy-induced sexual dysfunction diagnosis, evaluation, and a patient-centered approach to toxicity preventive strategies and management.
Citation
Rogers MJ, Ramirez-Fort MK, Kashanian JA, Broster SA, Matta J, Mahase SS, Fort DV, Niaz MJ, McClelland S 3rd, Bander NH, Fort M, Lange CS, Schlegel P, Mulhall JP. Prostatic irradiation-induced sexual dysfunction: A review and multidisciplinary guide to management in the radical radiotherapy era (Part II on Urological Management). Rep Pract Oncol Radiother. 2020 Jul-Aug;25(4):619-624. doi: 10.1016/j.rpor.2020.03.011. Epub 2020 May 6. PMID: 32549795; PMCID: PMC7286930.