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Supraventricular Tachycardia as an Initial Manifestation of Malignancy-Related Cardiac Invasion: A Case Report
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Cureus
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2025-10-15
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Abstract
Cardiac tumors are exceedingly rare, with metastatic lesions occurring more frequently than primary tumors. These tumors generally present with non-specific symptoms, reflecting tumor location and invasion of adjacent structures, and diagnosis is frequently incidental. A 66-year-old male smoker presented with hemoptysis and weight loss. Echocardiography revealed external invasion and compression of the left atrium by a left lung mass. His hospital course was complicated by recurrent supraventricular tachycardia (SVT). CT imaging showed a necrotic lung mass infiltrating the left atrium and pericardium, and biopsy confirmed invasive pulmonary adenocarcinoma. Atrial tachyarrhythmias via direct malignancy-related cardiac infiltration as an initial presentation of cancer are exceedingly rare and can significantly delay diagnosis and treatment due to vague symptoms. However, this entity can lead to life-threatening arrhythmia, underscoring the importance of early diagnosis and management. This case highlights the importance of considering malignancy-related cardiac invasion in patients with underlying malignancy with new-onset arrhythmias, as with our case with pulmonary adenocarcinoma and potentially life-threatening SVT through direct pericardial and atrial infiltration and involvement.
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Tumkur Panduranga V, Abdulfattah A, Gorantla A, Freitas De Souza V, Salciccioli L, McFarlane SI, John S. Supraventricular Tachycardia as an Initial Manifestation of Malignancy-Related Cardiac Invasion: A Case Report. Cureus. 2025 Oct 15;17(10):e94666. doi: 10.7759/cureus.94666. PMID: 41246575; PMCID: PMC12618099.