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In vitro activities of gemifloxacin (SB 265805, LB20304) against recent clinical isolates of Chlamydia pneumoniae.
Journal Title
Antimicrobial agents and chemotherapy
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Publication Date
1999-11
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Publication Volume
43
Publication Issue
11
Publication Begin
2806
Publication End
7
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aac.43.11.2806.pdf
Adobe PDF, 35.84 KB
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Abstract
We compared the in vitro activity of gemifloxacin, a new quinolone antibiotic, to the activities of levofloxacin, moxifloxacin, trovafloxacin, erythromycin, and doxycycline against 20 isolates of Chlamydia pneumoniae. Gemifloxacin was the most active quinolone tested, with a MIC at which 90% of the isolates are inhibited and a minimal bactericidal concentration at which 90% of strains tested are killed of 0.25 microg/ml, but this activity was less than those of doxycycline and erythromycin.
Citation
Roblin PM, Reznik T, Kutlin A, Hammerschlag MR. In vitro activities of gemifloxacin (SB 265805, LB20304) against recent clinical isolates of Chlamydia pneumoniae. Antimicrob Agents Chemother. 1999 Nov;43(11):2806-7. doi: 10.1128/AAC.43.11.2806. PMID: 10543770; PMCID: PMC89566.