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Review of The Use of 5-Fluorouracil as a Chemotherapy Drug to Treat Colorectal Adenocarcinoma

Cincotta, Melissa
; 
Wanits, Lyndsey
; 
Whittaker, Jeremy
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2017
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Student Research Showcase - April 12th and 13th, 2017
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https://hdl.handle.net/20.500.12648/83417
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Colorectal Adenocarcinoma is a cancer isolated in the colon and rectum. It is the third most commonly diagnosed cancer in the United States[14].This cancer does not occur suddenly as it takes years to develop and tends to be caused by changes to the lining of the colon or rectum [4]. The p53 protein, that regulates the cell cycle to prevent mutations, is most commonly effected by colorectal adenocarcinoma by causing mismatch DNA repair sequence. [3]
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