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In vitro activity of a group of broad-spectrum cephalosporins and other beta-lactam antibiotics against Chlamydia trachomatis.
Journal Title
Antimicrobial agents and chemotherapy
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1983-03
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Publication Volume
23
Publication Issue
3
Publication Begin
493
Publication End
4
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aac.23.3.493.pdf
Adobe PDF, 328.88 KB
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Abstract
The activities of seven broad spectrum cephalosporins, four other beta-lactam antibiotics, and one monobactam against Chlamydia trachomatis were measured in a cell culture system. The minimal inhibitory concentration of four of the seven cephalosporins was greater than or equal to 128 micrograms/ml; those of the other three were from 16 to 32 micrograms/ml. Of the other agents, only mecillinam had activity against C. trachomatis comparable to that reported for ampicillin (minimal inhibitory concentration, less than or equal to 0.5 micrograms/ml).
Citation
Hammerschlag MR, Gleyzer A. In vitro activity of a group of broad-spectrum cephalosporins and other beta-lactam antibiotics against Chlamydia trachomatis. Antimicrob Agents Chemother. 1983 Mar;23(3):493-4. doi: 10.1128/AAC.23.3.493. PMID: 6847175; PMCID: PMC184677.